Protein Alignment alpha-Est4 and ace-3

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_496963.1
• Gene: ace-3 / 175076
• WormBaseID: WBGene00000037
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 145/571 - (25%)
• Similarity: 227/571 - (39%)
• Gaps: 158/571 - (27%)

  Fly    12 VQTTHGKVRGILLKSLY-DEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ- 74
            |||..|.|||  .:|.: :::..:|.|:|:|.||:...|||:|...:||:|....:.....|.|
 Worm    34 VQTKLGTVRG--TESDHGNKRVRSFLGVPFAEPPINEHRFKKPTPARPWNGTISANTLSPACFQG 96

  Fly    75 ----------VSTLTKEVEGSEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAW-GPDY 128
                      ..........||||||:||.... :...:.|:|::.||.|..|..|...: |.:.
 Worm    97 RDSYDPTFWGSEMWNANTPVSEDCLYVNIWAPA-DAYNLTVLVWLFGGGFWYGSPSLLLYDGKEL 160

  Fly   129 FMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
            ..:.||:.::|.:|:||.|:|.|:..|  ||||.|:.|..|||.|||.:..:|.|:|.||::.|.
 Worm   161 ATRGNVIVVNINYRVGPFGYLFLDHED--VPGNMGMLDQQLALYWIRDHIFSFGGNPARISLVGE 223

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLAG-----FSMEL-NRLPQMEYRLAKHLGYEGDNVDSQV- 251
            |:|:.::...|.:|.|:|||...||.:|     :||:. .|..|....||..:|.....:..|.
 Worm   224 SAGAASIVAHLIAPASKGLFQNGILQSGSLDNKWSMDSPKRAKQKSTALADLVGCNQTKITDQTA 288

  Fly   252 ---------------------LEFLLKADPALIVSAD--FFTPLEKRQGHNMPFKPSIESYSTPN 293
                                 |||     |..|||.|  ||..|:   |.
 Worm   289 CLRNTPAQLLIDNIWNVGLNFLEF-----PFAIVSKDQNFFKHLD---GF--------------- 330

  Fly   294 AVLLAEPIDLQRTTWSNRIPIILGANSGEG--MSIFSFVK------MNPSWLKE---------FQ 341
                   |.|:..|:|..:.::.|.|..||  .:|::..|      :.|...::         |.
 Worm   331 -------IALREGTYSTDVNLMFGINHDEGNFWNIYNLAKFFDKQSVKPGLDRDEFHECVDTAFA 388

  Fly   342 CNPERVL---------PWTLRNRC-DPGQR-----RQLGQALIHHFCEAHGHELTVDHTNGLVEL 391
            ..||.|.         |     :| ||.::     .|:.|.:..:|       .|.|..     .
 Worm   389 VQPELVRTAAKYVYSDP-----KCTDPKKKTDFYTEQVNQMVGDYF-------FTCDSI-----W 436

  Fly   392 FTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDS-----PDFNFYRIRFMGKEQRGVGHVDELGYI 451
            |.|.:         .::...|:..::|.||..|     |.:.            ||.|..|:.|:
 Worm   437 FAHNY---------PKMAGNQSNVFVYYFDQPSSANPWPKWT------------GVMHGYEIEYV 480

  Fly   452 FKLPA-TFKLDKSRPEFTAIRRLVAMFVQFAATSDPN----APLTKSLVDW 497
            |.:|. ......::.|.....:::..:..||.|..|:    |..|...:.|
 Worm   481 FGVPLHNTTAGYTKEEMDVSEKVIDFWTTFANTGVPSLRKRAVGTTQKIKW 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	145/571 (25%)
ace-3	NP_496963.1	COesterase	33..564	CDD:395084	145/571 (25%)