Protein Alignment alpha-Est4 and ace-4

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 150/601 - (24%)
• Similarity: 247/601 - (41%)
• Gaps: 142/601 - (23%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQV 75
            |::|..|.::|.....| .::...|.|:|:|.|.:...||::|.:.|.|.|:.|.:||.:.|.|.
 Worm    28 VLETKLGDIKGTEFFFL-SKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDATKPANACFQT 91

  Fly    76 -----------STLTKEVEGSEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAW-GPDY 128
                       .......:.|||||||||.... :...:.|||:..||.|..|..|...: |...
 Worm    92 RDNYNTSFWGSEMWNANTQISEDCLYLNIWAPA-DAYNLTVMVWFFGGGFYSGSPSLSIYDGKAL 155

  Fly   129 FMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
            ...:||:.::|.:||||.|||.|..||  .|||.||.|..|||.|:|.|..:|.|:|:::.:||.
 Worm   156 TSTQNVIVVNINYRLGPFGFLYLGHPD--APGNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFGQ 218

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLAGFSME----LN---RLPQMEYRLAKHLGYEGDNVDSQV 251
            |:|:.::...|.:|.|.|||..|||.:| |:|    :|   |..|...:|.:.:|.....||:.:
 Worm   219 SAGAASIVAHLIAPGSRGLFKNAILQSG-SLENTWAINSPFRAKQKSEKLLELVGCNKTTVDTSM 282

  Fly   252 ----------------------LEFLLKADPALIVSAD--FFTPLEKRQGHNMPFKPSIESYSTP 292
                                  |||     |.:|||.|  ||       ||       :::::.
 Worm   283 ACLRLVSPEQLSLSTWNISLTYLEF-----PFVIVSRDKHFF-------GH-------LDAHAA- 327

  Fly   293 NAVLLAEPIDLQRTTWSNRIPIILGANSGEG--MSIFS----FVKMNPSWLK--EFQCNPER--- 346
                      |:...::..:.:::|.|..||  .:|:.    |.|.:|..|.  ||....:|
 Worm   328 ----------LREGDFNRDVNLMIGMNKDEGNYWNIYQLPQFFDKADPPELNRTEFDFLIDRTFS 382

  Fly   347 VLPWTLRNRC-----DPGQRRQLGQALIHHFCEAHG----------HELTVDHTNGLVELFTHGF 396
            :.|..:|:..     ||.             |..||          :::..|:......|:....
 Worm   383 IQPDIIRSAAKYIYSDPN-------------CTDHGRKTRFYAGQMNQIVGDYFFSCDSLWLADQ 434

  Fly   397 VHAMDRLIQSRLTYGQAPTYLYRFDFDS-----PDFNFYRIRFMGKEQRGVGHVDELGYIFKLPA 456
            ..::.|:..|.........::|.|...|     |.:.            |..|..|:.|:|.:|.
 Worm   435 FRSIPRVKSSSPQRKPGKVFVYHFTQSSSANPWPKWT------------GAMHGYEIEYVFGIPL 487

  Fly   457 TFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKR-----MVLNISEELK 516
            ::..:..|.|....|:::..:..||....|...:.|:...|   ..|.::     |.|.....::
 Worm   488 SYSKNYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSEHW---PEFNEQNHYRWMQLRSGSNIR 549

  Fly   517 FIPQPEMPKLKFFDRL 532
            .|...:..:.:|:.|:
 Worm   550 PIKPKKQVECQFWRRV 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	148/596 (25%)
ace-4	NP_496962.1	COesterase	28..562	CDD:395084	148/596 (25%)