Protein Alignment alpha-Est4 and ace-2

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 144/602 - (23%)
• Similarity: 233/602 - (38%)
• Gaps: 147/602 - (24%)

  Fly    11 VVQTTHGKVRGILLKSLYD-EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC-L 73
            ||.|..|.:||:  ...:| .:..||.|:|||.||:|:.|||....:..|.|..:.......| |
 Worm    40 VVHTPLGTIRGV--GQTFDGAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTCYL 102

  Fly    74 QVSTLTKEVEG----------SEDCLYLNISV-KTLNGDPMPVMVYIHGGAFKGGDSSRRAW-GP 126
            .:.:...:..|          |||||.:||.| :..:|.   |||:|:||.|..|..|...: |.
 Worm   103 TIDSAFPQFPGAEMWNPPGAISEDCLNMNIWVPEDHDGS---VMVWIYGGGFFSGTPSLDLYSGS 164

  Fly   127 DYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIF 191
            .:..||:.:.:::.:||||.|||...| |..:.||.||.|..|||||:..|...|.||..|:|:|
 Worm   165 VFAAKEHTIVVNVNYRLGPFGFLYFGD-DSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLF 228

  Fly   192 GHSSGSMTVQLLLASPQSEGLFHRAILLAG------FSMELNRLPQMEYRLAKHLGYEGDNVDSQ 250
            |.|:||.:....|.:|.|...|...|..:|      .|.....:..:.:||||.:.....::::.
 Worm   229 GESAGSASTTAHLFAPNSHKYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDMNAI 293

  Fly   251 VLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPID------------- 302
            |.  .|::.||.:|.|:               ..:|.....|.......|:.
 Worm   294 VK--CLRSVPAHLVQAE---------------ADNISGDIGPPMTFAYVPVSSDANFFQGDVFQK 341

  Fly   303 LQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPE----------------RVLPWT 351
            |....:...:.||.|:...||          ..||..:...|:                |.|  .
 Worm   342 LANKQFKKDVNIIFGSVKDEG----------TYWLPYYMSLPKYGFAFNHTISAEDPHNRAL--I 394

  Fly   352 LRNRCDPGQRRQL-----GQALIHHFCEAHGHELTVD-----HTNGLVE-----LFTHGFVHAMD 401
            .|:..:...|..:     .:.:::.|..::.|..|.:     :.:|:..     .||...:...|
 Worm   395 TRDHYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSNVPEERYRDGVARFLGDLFFTCSLIDFAD 459

  Fly   402 RLIQSRLTYGQAPTYLYRFDFDS-----PDFNFYRIRFMGKEQRGVGHVDELGYIFKLP------ 455
             ||...: :|.  .|:|.|.:.|     |.:            .||.|..|:.|.|..|
 Worm   460 -LISDNI-FGN--VYMYYFTYRSSANPWPKW------------MGVMHGYEIEYAFGQPYWRPHL 508

  Fly   456 --ATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNA------PLTKSLVDWKPVTRFGKRMVLN-- 510
              .|...|:.|  .::|  ::.::..||.|...::      .:.:..::....|..||..:::
 Worm   509 YDQTHLEDEKR--LSSI--IMQIWANFANTGRTDSFWPQYNKIERKAIELGETTLQGKHRIISDV 569

  Fly   511 -------ISEELKFIPQ 520
                   |.|...|:.|
 Worm   570 HGGFCRMIDEAKAFVKQ 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	144/602 (24%)
		Aes	<104..>219	CDD:223730	47/115 (41%)
ace-2	NP_491141.1	COesterase	33..546	CDD:278561	137/560 (24%)
		Aes	<135..>233	CDD:223730	41/101 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910