Protein Alignment alpha-Est4 and cest-27

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 154/530 - (29%)
• Similarity: 233/530 - (43%)
• Gaps: 103/530 - (19%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ- 74
            |...|.|.::|:..:.........|.|||||.||:|.||||:|...:.|....||.:...:..|
 Worm    27 VHDATCGPIKGVGYEQEDGSVVEGFLGIPYAEPPIGALRFKKPVAHRKWTEPLDCVRFGPRSPQN 91

  Fly    75 -------VSTLTKEVEGSEDCLYLNISVKTLNG----DPMPVMVYIHGGAFKGGDSSRRAWGPDY 128
                   |:|:.|   ..|.||.||:.......    |..||||:||||.|....||      :|
 Worm    92 DELLGQFVNTVGK---SEEHCLSLNVFTPKWESNEWPDGFPVMVFIHGGGFAVHSSS------NY 147

  Fly   129 --------FMKENVVYISIGHRLGPLGFLSLNDPDLEV-PGNAGLKDVILALRWIRANAANFNGD 184
                    ...::||.::|.:|||.|||.:..|   || .||.||.|...||.|::.|..:|.||
 Worm   148 GCASIARNLCTKDVVVVTINYRLGVLGFFTTGD---EVCRGNLGLWDQTAALEWVQENIQSFRGD 209

  Fly   185 PERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG-----FSMELN-RLPQMEYRLAKHLGYE 243
            |:.:||||.|:|..:|.||..||.|.|||:|||.:||     |:|..: :..|:....|::||:|
 Worm   210 PDNVTIFGQSAGGASVDLLCLSPHSRGLFNRAIPMAGNGECDFAMRTSEQQAQLSREFARYLGWE 274

  Fly   244 GDNVDSQ-VLEF-----LLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPID 302
            ||:.||: :|:|     |.|.:..:.....|    :..|..::.|.|:.:....|      :|::
 Worm   275 GDDNDSEDLLQFIDQQPLYKIEMGINPKRGF----KHSQAGSLYFVPNFDGDFFP------KPLN 329

  Fly   303 LQRTTWSNRIPIILGANSGEGMSIFSF--VKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLG 365
            ..|.. :.::.|:.|....||:...:.  :..||..:|:|.   .|:.     ..||.|:|....
 Worm   330 QLRKE-APKMQIMTGTTKYEGLFFIALGALSKNPEGIKKFM---GRIF-----KECDYGERADDV 385

  Fly   366 QALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLI-QSRLTYG-----------QAPTYLY 418
            ..:::.|.....|  ..||...:         |.:.:.| ...:.||           |...|.|
 Worm   386 LQMVYDFYFKGVH--PKDHEKNM---------HQIVKFIGDYSINYGTYRLANIMTDLQHDVYFY 439

  Fly   419 RFDF-DSPDFNFYR--IRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAM---F 477
            :||: :|..|..:|  :.|:|..     |..|:.|:.   ....:.|.||.....:.|..|   |
 Worm   440 QFDYHNSAGFGVFRWLLPFLGST-----HCTEMRYVL---GKGIISKFRPNDNDKKMLHVMTTYF 496

  Fly   478 VQFAATSDPN 487
            ..||...:||
 Worm   497 TNFAKYGNPN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	154/530 (29%)
cest-27	NP_871861.2	COesterase	29..548	CDD:395084	153/528 (29%)