Protein Alignment alpha-Est4 and Ces2c

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 170/606 - (28%)
• Similarity: 256/606 - (42%)
• Gaps: 150/606 - (24%)

  Fly     5 YNEDAP---VVQTTH-GKVRGILLKSLYDEQ--FYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIR 63
            :.:|:|   .::||| |:||| .|..:.|.:  .:.|.|||:|..|:|.|||..|.|.:||.|:|
  Rat    25 WGQDSPESSSIRTTHTGQVRG-KLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVR 88

  Fly    64 DCSKPLSKCLQ------------VSTLTKEVEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAF 114
            |.:...:.|||            :..:...:..|||||||||  ......|..:||||.|||||.
  Rat    89 DGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGAL 153

  Fly   115 KGG-----DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWI 174
            ..|     |.|..|      :.|::|.::|.:|||.|||.|..|.  ...||.|..|.:.||||:
  Rat   154 VIGMASMCDGSLLA------VNEDLVVVAIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWV 210

  Fly   175 RANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQM------- 232
            :.|.|:|.|:|.|:||||.|:|..:|...:.||.|:||||.||:.:|.::    ||.:
  Rat   211 QQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVAL----LPDLISETSET 271

  Fly   233 -EYRLAKHLGYEGDNVDSQVLEFLLKADPA---LIVSADFFTPLEKRQGHNMPFK--PSIESYST 291
             ...:||..|.|.  .||:.|...|:|...   |::              |..||  |::    .
  Rat   272 VSTTVAKLSGCEA--TDSETLVRCLRAKSGAEILVI--------------NKVFKMIPAV----V 316

  Fly   292 PNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEF-QCNPERVLPWT---- 351
            ....|...|.:|..:...:.:|.|:|.|:.|.......|......:||. :.|.:.||..|
  Rat   317 DGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQM 381

  Fly   352 --------------LRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDR 402
                          :.|..||       |.|...:.|..|                 .|:..:..
  Rat   382 MLPPECGDLLMEEYMGNTDDP-------QTLQIQYAEMMG-----------------DFLFVIPA 422

  Fly   403 LIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATF----KLDKS 463
            |..:......||.|.|.|. .:|.: |..:|   .......|.||:.::|   .:|    |:|.:
  Rat   423 LQVAHFQRSHAPVYFYEFQ-HAPSY-FKNVR---PPHVKADHADEVPFVF---GSFFWGIKVDFT 479

  Fly   464 RPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEE-LKFIPQPEMP--- 524
            ..|....||::..:..||...:||   ::.|..|.         ||:..|: |:...||.:.
  Rat   480 EEEKLLSRRMMKYWANFARHGNPN---SEGLPYWP---------VLDHDEQYLQLDTQPAVDRAL 532

  Fly   525 ---KLKFF-----DRLYEMAG 537
               :|:|:     .::.|:.|
  Rat   533 KARRLQFWTKTLPQKIQELNG 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	167/588 (28%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	165/584 (28%)