Protein Alignment alpha-Est4 and LOC1281827

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_061505289.1
• Gene: LOC1281827 / 1281827
• VectorBaseID: AGAMI1_012788
• Length: 737
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 169/587 - (28%)
• Similarity: 259/587 - (44%)
• Gaps: 113/587 - (19%)

  Fly     2 SDDYNEDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCS 66
            ||..:.|..||.|..|::|||.:.:...::...:.|||||.||:|.|||:.|...:.|.|:.:.:
Mosquito   158 SDANDNDPLVVNTDKGRIRGITVDAPSGKKVDVWLGIPYAQPPVGPLRFRHPRPAEKWTGVLNTT 222

  Fly    67 KPLSKCLQ-VSTLTKEVEG----------SEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSS 120
            .|.:.|:| |.|:..:..|          ||||||:|:...........||::|.||.|..|.::
Mosquito   223 TPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIFGGGFYSGTAT 287

  Fly   121 -----RRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAAN 180
                 .||...:    |||:.:|:.:|:..||||.|..|  |.||||||.|..|||||:|.|...
Mosquito   288 LDVYDHRALASE----ENVIVVSLQYRVASLGFLFLGTP--EAPGNAGLFDQNLALRWVRDNIHR 346

  Fly   181 FNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG--------FSMELNRLPQMEYRLA 237
            |.|||.|:|:||.|:|:::|.|.|.|..|..||.||||.:|        .|.|...|..:  |||
Mosquito   347 FGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSREEATLRAL--RLA 409

  Fly   238 KHLG--YEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQG-HNMPFKPSIESYSTPNAVLLAE 299
            :.:|  :|...: |..:|.|...||.::|:.::.|     .| ...||.|.::     .|.|...
Mosquito   410 EAVGCPHEPSKL-SDAVECLRGKDPHVLVNNEWGT-----LGICEFPFVPVVD-----GAFLDET 463

  Fly   300 PIDLQRTTWSNRI---PIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLR-------- 353
            |   ||:..|.|.   .|:.|:|:.||.....:      :|.|.....|.|   |:.
Mosquito   464 P---QRSLASGRFKKTEILTGSNTEEGYYFIIY------YLTELLRKEEGV---TVTREEFLQAV 516

  Fly   354 NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLY 418
            ...:|.......||::..:.:    ....|:.|...:        |:|:::..           |
Mosquito   517 RELNPYVNGAARQAIVFEYTD----WTEPDNPNSNRD--------ALDKMVGD-----------Y 558

  Fly   419 RFDFDSPDF---------NFYRIRFMGKEQ-------RGVGHVDELGYIFKLPATFKLDKSRPEF 467
            .|..:..:|         |.|...:..:.:       .||.|.||:.|:|..|....|..:..|.
Mosquito   559 HFTCNVNEFAQRYAEEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNPTLGYTEDEK 623

  Fly   468 TAIRRLVAMFVQFAATSDPNAPLTKS--LVDWKPVTRFGKRMVLNISEELKFIPQ-PEMPKLKFF 529
            ...|:::..:..||.|.:|| |.|.|  ..:|...|..| |..|.:.....|:.: |.:.:..|:
Mosquito   624 DFSRKIMRYWSNFAKTGNPN-PNTASSEFPEWPKHTAHG-RHYLELGLNTSFVGRGPRLRQCAFW 686

  Fly   530 DR 531
            .:
Mosquito   687 KK 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	166/577 (29%)
LOC1281827	XP_061505289.1	None