Protein Alignment alpha-Est4 and LOC1280747

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_061513099.1
• Gene: LOC1280747 / 1280747
• VectorBaseID: AGAMI1_007562
• Length: 1118
• Species: Anopheles gambiae
• Alignment Length: 627
• Identity: 173/627 - (27%)
• Similarity: 257/627 - (40%)
• Gaps: 168/627 - (26%)

  Fly    11 VVQTTHGKVRGILLK--SLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            :|.|..|.:||::|:  |.:.|....|..:|||.||:|:|||:.|..|.||.|.:......|.|.
Mosquito    74 IVDTKSGAIRGVILELNSKHLEPVEVFKAVPYATPPIGSLRFEPPKKLPPWKGTKLADTFGSVCP 138

  Fly    74 Q----VSTLTKEV-------------------EGSEDCLYLNISV-----KTLNGDPMPVMVYIH 110
            |    :|..|..:                   ..|||||.|||.|     :.|.. |..:..|||
Mosquito   139 QSFPDISNRTAALLSMPKGRYQHLKRLQPLLANQSEDCLTLNIYVPGSGSRGLEA-PYSIFFYIH 202

  Fly   111 GGAFKGGD------SSRRAWGPDYFMKENVVYISIGHRLGPLGFL----SLNDPDLEVPGNAGLK 165
            |.|:..|.      |...::|       :|:.:::..|||.||||    ||:...   .||.||.
Mosquito   203 GEAYDWGSGNPYDGSVLASYG-------HVIVVTVNFRLGILGFLKTRASLSPGS---GGNLGLM 257

  Fly   166 DVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSM------ 224
            |:||||:|:|.|.|:|.|||:||||.||.:|:....|.|.|...:||..|||||:|.::
Mosquito   258 DIILALQWVRDNIASFGGDPKRITIVGHDTGAALANLALISKAGKGLVQRAILLSGSALSPWALI 322

  Fly   225 ---ELNRLPQMEYRLAKHL--GYEGDNVDSQVLEFLLKADP--AL----IVSADF------FTPL 272
               :..|| ::..::|.||  |..|....:..:...|:..|  ||    :.|..|      |.||
Mosquito   323 PDPDAVRL-EVSQQMACHLVPGRNGRKPTTDDITECLRDKPIEALMGVRLTSVRFMPSWGPFLPL 386

  Fly   273 EKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWL 337
            |.........:.|.|.:.|..                    ::||..:.|..|.||...:... |
Mosquito   387 EDSMDPEFAMEHSGEGFITSE--------------------LMLGMTTTESYSDFSASDIQYG-L 430

  Fly   338 KEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCE---AHGHELT-----VDH----TNGLVE 390
            :|.|.|  |:|...:||            |...|..|   |..:|.|     :.|    .:..:|
Mosquito   431 EEDQRN--RLLRTYIRN------------AFTFHLNEIFSAVRNEYTDWDKPIQHPINIRDSTME 481

  Fly   391 LFTHGFVHAMDRLIQSRLTYGQ--APTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFK 453
            ..:.|  |.:..:|:....:.:  |.||::.|.:.|.:..:       .::.|....::|.|||.
Mosquito   482 ALSDG--HTVAPIIKVAYLHARRGAKTYMFHFGYQSKESEY-------PQRLGSVRGEDLPYIFG 537

  Fly   454 LP-----ATFKLDKSRPEFTAIRRLVAMFVQFAATSDPN-------APLTKSLVDWKPVTRFGKR 506
            ||     ..|..:.||.:......::.....|..|.|||       |||.......|..|||  |
Mosquito   538 LPLVQGGPVFPQNYSRQDMGVNEAVLNFVTNFCKTGDPNEAGHQQAAPLHPDYGTAKERTRF--R 600

  Fly   507 MV------------LNISEELKFIPQPEMPKLKFFDRLYEMA 536
            ::            |:||.:         ||::...|.::||
Mosquito   601 LITWETYETTTQQYLSISTK---------PKMRSHYRGHKMA 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	170/618 (28%)
LOC1280747	XP_061513099.1	None