Protein Alignment alpha-Est4 and LOC1273105

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_312052.3
• Gene: LOC1273105 / 1273105
• VectorBaseID: AGAMI1_000342
• Length: 554
• Species: Anopheles gambiae
• Alignment Length: 578
• Identity: 174/578 - (30%)
• Similarity: 259/578 - (44%)
• Gaps: 103/578 - (17%)

  Fly     8 DAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC 72
            |.|::.|:.|:|:|..........:|:|.|||||.||:|.|||.:|.....|.|:||.|:..|.|
Mosquito    23 DRPIIGTSSGQVQGTTEDCGLFCTYYSFKGIPYAEPPVGALRFADPVPRAAWTGVRDASQHGSSC 87

  Fly    73 LQVSTLTKEVEGSEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVVYI 137
            .....|..|   :|||||||:...:|.| ..||||::||||:.||......:|..|||.||||.:
Mosquito    88 PTPDALPAE---AEDCLYLNVYSPSLVG-TRPVMVFVHGGAYVGGSGDDALYGARYFMPENVVIV 148

  Fly   138 SIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQL 202
            ::.:|||.||||...  |....||..:||.:.||||::.|...|.||..|:||||.|:|...|..
Mosquito   149 TLNYRLGVLGFLGTG--DRSASGNWAIKDCVEALRWVQRNIGAFGGDAGRVTIFGQSAGGALVHF 211

  Fly   203 LLASPQSEGLFHRAILLAG-----FSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPAL 262
            |..||.:.|||.|||..:|     :|::.|...|.| ::|..||             :...|.|.
Mosquito   212 LTLSPLAVGLFERAITHSGSAINSWSLQPNPRQQAE-KIAAELG-------------IHTTDTAT 262

  Fly   263 IVSA-------DFFTPLEKRQGHNM---PFKPSIESYSTPNAVLLAE-PIDLQRTTWSNRIPIIL 316
            :|||       |..:|.:......|   .|.|.:|...||..|.|.. ||:|..:.....:|::.
Mosquito   263 LVSALRQVPYRDLISPDQTTLDELMVPLAFGPVVEPADTPGQVALDRLPIELIESGSYRAVPLMA 327

  Fly   317 GANSGEGMSIFSFVKM--NPSWLKEFQCNPERVLP--WTLRNRCDPG-----------------Q 360
            |....:.: :||.|:|  ||.....|..||..::|  |.:     |.                 |
Mosquito   328 GFTDMDAL-LFSAVEMVTNPGIFDTFNNNPHLLVPFVWNI-----PAGSAASSAVSQAFRQYYWQ 386

  Fly   361 RRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSP 425
            .:.|..||:..|                 .::......|..:|..::....::..|||:|.:|.
Mosquito   387 SQPLSPALLAQF-----------------SVYLTDLQFAYPQLEMAKRHASRSSVYLYQFKYDG- 433

  Fly   426 DFNFYRIRFMGKEQRGVGHVDELGYIF--------KLPATFKLDKSRPEFTAIRRLVAMFVQFAA 482
            |.|..: :|.|....|..|.|:|.|:|        :||.|      ....|..:|::.::..||.
Mosquito   434 DLNLVK-QFAGIPLPGAIHGDDLCYLFETKQFGGGELPIT------SHAATVRQRMLRLWTNFAR 491

  Fly   483 TSDPNAPLTKSLVD---WKPVTRFGKRMVLNISEELKFIPQPEMPKLKFFDRLYEMAG 537
            ..:| .|...:|:.   |:|::.......|||..:|.....|...:   :.:..::||
Mosquito   492 DGNP-TPTADALLQGTLWRPLSPGMIDATLNIGHDLTMEVNPIASR---YSQWLDLAG 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	172/568 (30%)
LOC1273105	XP_312052.3	COesterase	25..540	CDD:395084	171/569 (30%)