Protein Alignment alpha-Est4 and LOC1270332

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_309019.5
• Gene: LOC1270332 / 1270332
• VectorBaseID: AGAMI1_001880
• Length: 690
• Species: Anopheles gambiae
• Alignment Length: 539
• Identity: 182/539 - (33%)
• Similarity: 252/539 - (46%)
• Gaps: 83/539 - (15%)

  Fly     7 EDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSK 71
            |....|....|.:.|:.........:|.|.|||||.||:|:||||.|             .||.
Mosquito   145 ESKITVSIRPGNIVGLKRALPNGTDWYVFKGIPYAQPPVGSLRFKPP-------------VPLD- 195

  Fly    72 CLQVSTLTKEVEG-------------SEDCLYLNI-SVKTLNGDPMPVMVYIHGGAFKGGDSSRR 122
            .|..|.|...|:|             ||||||||: |.:.....|:||||:||||.|..|.|...
Mosquito   196 TLPTSPLECFVDGPSCYSEDVRFQRMSEDCLYLNVYSPQLQPKTPLPVMVWIHGGGFYVGTSDSA 260

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            .:.|.|.:::..|.:.|.:||||||||||  |...|.||.||||..::|||:|.|.|.|.|||..
Mosquito   261 LYEPPYLVQQGAVVVCINYRLGPLGFLSL--PSAGVDGNMGLKDQRMSLRWVRDNIAQFGGDPHN 323

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQME-----YRLAKHLGYEGDNV 247
            :|:||.|:|..:|.|...|..|...|||||..:|.:.. :.|.|.|     .:||:.||.|..:.
Mosquito   324 VTLFGESAGGASVHLHYLSEVSRAYFHRAIAQSGTAFN-DWLWQREPADRARKLARLLGGEESDT 387

  Fly   248 DSQVLEFLLKADPALIVSADFFTPLEKR----QGHNM----PFKPSIESYSTPNAVLLAEPIDLQ 304
            |..||..|:.|      ||:..|.|:.:    :...|    ||.|.||.....:|::...|....
Mosquito   388 DEAVLATLMGA------SAEQMTALQNQCMSERDQTMLVRFPFTPVIERVGAVDAIITEHPARAA 446

  Fly   305 RTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALI 369
            ..|::|.||::||:.|.||:.:..|||..   |..:|.:|.|::|.||....:. |.|....|::
Mosquito   447 EKTFANPIPLMLGSTSDEGLVLRGFVKEK---LPLYQTDPTRLIPVTLALDSEE-QERSARDAIV 507

  Fly   370 HHF------CEAHGHELTV---DHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSP 425
            ..|      .|....::|.   |:.|.|     .|::.|     :....:..||.|:|.|.....
Mosquito   508 KFFFQERPIAEETMRKITTILGDNLNTL-----PGYIAA-----ELHARFQSAPLYMYVFSHMGA 562

  Fly   426 DFNFYRIRF-MGKEQRGVGHVDELGYIF--KLPATFKLDKSRPEFTAIRRLVA-MFVQFAATSDP 486
             .|.||..: :..|:.|..|.|||.|:|  .|..|..: :...|....|.... ::|.||...:|
Mosquito   563 -LNKYREEYKIPPEEVGAVHADELYYLFSSSLYNTAAV-QDHTESGRFREYCCNLWVNFARFGNP 625

  Fly   487 NAPLTKSLVDWKPVTRFGK 505
            :|    :||||.||.|..|
Mosquito   626 HA----TLVDWAPVERPAK 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	181/538 (34%)
LOC1270332	XP_309019.5	None