Protein Alignment alpha-Est4 and LOC1270129

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_308801.4
• Gene: LOC1270129 / 1270129
• VectorBaseID: AGAMI1_007698
• Length: 641
• Species: Anopheles gambiae
• Alignment Length: 631
• Identity: 145/631 - (22%)
• Similarity: 227/631 - (35%)
• Gaps: 180/631 - (28%)

  Fly     8 DAPVVQ-TTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEP--HDLKPWHGIRDCSKPL 69
            |.|.|. ...|.|.|:.:|....::..|:.|||||..|:...||..|  .:|..|.|:::.:...
Mosquito    30 DPPTVTIPDQGTVMGMYMKMFRTQRVVAYLGIPYAQAPVNEKRFTPPVVDNLPSWEGVKNATSSA 94

  Fly    70 SKCLQV--------STLTKEV----------------EGSEDCLYLNISV--KTLNGDPMPVMVY 108
            ..|..:        :.|..|:                :..||||:|||.:  .|:..|...|:|.
Mosquito    95 PHCWHMPRDTHRRHNQLFMELIRSGDDGGGGDGGGDRQYDEDCLFLNIYIPDSTMPTDGYSVLVT 159

  Fly   109 IHGGAFKGGDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRW 173
            ...|.| .||:...........|:.::.:::.:|||..||.:  ..|.|.|||.||.|...||.|
Mosquito   160 FPTGDF-DGDTPFTLNPFQMVFKQKIIVVTVAYRLGIFGFFT--SMDGEAPGNFGLMDQSAALLW 221

  Fly   174 IRANAANFNGDPERITIFGHSSGSMTVQLLLASPQ-SEGLFHRAILLAGFSMELNRLPQMEYRLA 237
            |:.|...|||:...:||.||.:|::.|.|.|.|.. ::.:||:|||::|     :.|.....|.|
Mosquito   222 IKRNIRLFNGNEGSVTIMGHGTGAVCVGLHLTSGDWTDDMFHKAILMSG-----SLLLDSSVRTA 281

  Fly   238 KHLGYEGD---------------------NVDSQVL----------------------EFL---- 255
            |......|                     .||:|:|                      .|:
Mosquito   282 KQYASSLDELATAFGCFRRPTTKLMDCLRRVDAQILAENSPPIDWGPVIDQGLSNTTTPFIPDHP 346

  Fly   256 --------LKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPI--DLQRTTWSN 310
                    |:..|.||...|....||...|..:......|.:.|    ||.:.:  ||....::.
Mosquito   347 NMLVHQGKLRRVPLLIGHTDMEEVLELTMGDMLEHGLGAEMFDT----LLGDVVMSDLAEMEFNE 407

  Fly   311 RIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEA 375
               .:.|.|....|....:         :::..|....|..||.:                :.|.
Mosquito   408 ---TLCGGNMDIVMEAVQY---------QYKPYPPTTEPLALRRK----------------YIEF 444

  Fly   376 HGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDF---------DSPDFNFYR 431
            ......|..|   :||..|     |.:         ||.|::||||.         |.|
Mosquito   445 ATERKYVAPT---IELAMH-----MSQ---------QADTFVYRFDIKPRTAAALKDVP------ 486

  Fly   432 IRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRR----LVAMFVQFAATSDPNAPLTK 492
                  |..||.|..||.:::.||....|.......:|.:|    ::.::..||..::|..  ..
Mosquito   487 ------EWVGVPHNFELIFLWGLPYWLALADQMQWDSADKRVADIVMTLWANFAKFTNPTQ--VG 543

  Fly   493 SLVDWK--PVTRFGKRMV---LNISEELKFIPQPEMPKLKFFDRLY 533
            ..:.|:  .||..|..::   .|:|:....    ....:||::..|
Mosquito   544 VYIRWEKFTVTEPGVLIIDRSFNMSDHTTM----SFDAVKFWNHYY 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	143/625 (23%)
LOC1270129	XP_308801.4	None