Protein Alignment alpha-Est4 and Ces1g

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 535
• Identity: 156/535 - (29%)
• Similarity: 233/535 - (43%)
• Gaps: 90/535 - (16%)

  Fly    10 PVVQTTHGKVRG--ILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC 72
            |||.|.||||.|  :.|:. :.:....|.|:|:|.||||:|||..|...:||..::..:.....|
Mouse    24 PVVHTVHGKVLGKYVTLEG-FSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLC 87

  Fly    73 LQ----------VSTLTKEV---EGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGGDSSRR 122
            .|          :.|..:::   :.|||||||||  .........:||||:||||... .|.:..
Mouse    88 YQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLV-IDGAST 151

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            ..|....:.||||.:.|.:|||..||.|..|....  ||.|..|.:.||.|::.|.|||.|:|..
Mouse   152 YDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSR--GNWGHLDQVAALHWVQDNIANFGGNPGS 214

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYE--------- 243
            :||||.|:|..:|.:|:.||.::.||||||  |..|:..|  |.:..|.|:.|..:
Mouse   215 VTIFGESAGGESVSVLVLSPLAKNLFHRAI--AQSSVIFN--PCLFGRAARPLAKKIAALAGCKT 275

  Fly   244 ----------GDNVDSQVLEFLLKADPALIVSADFF-TPLEKRQGHNMPFKPSIESYSTPNAVLL 297
                      ....:.::||..||..   ..:.||. .|.|     :.||.|::     .:.|||
Mouse   276 TTSAAMVHCLRQKTEDELLEVSLKMK---FGTVDFLGDPRE-----SYPFLPTV-----IDGVLL 327

  Fly   298 AE-PIDLQRTTWSNRIPIILGANSGE-GMSIFSFVKMNPSWLKEFQCNPERVL--PWTLRNRCDP 358
            .: |.::......|.:|.::|.|..| |..|..|:....|..|..|.....:|  .:.:.|
Mouse   328 PKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILN---- 388

  Fly   359 GQRRQLGQALIHHFCEAH--GHELTVDHTNGLVELFTHGFVHAMDRLIQSRL-TYGQAPTYLYRF 420
                 :.:.||....|.:  |.|.....|:..::|. ...:..:..:|.||. ....||||:|.:
Mouse   389 -----ISEKLIPAAIEKYLGGTEDPATMTDLFLDLI-GDIMFGVPSVIVSRSHRDAGAPTYMYEY 447

  Fly   421 DFDSPDFNFYRIRFMG--KEQRGVG-HVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAA 482
            .        ||..|:.  :.|..:| |.|||..::..| ..|...|..|....:.::..:..||.
Mouse   448 Q--------YRPSFVSDDRPQELLGDHADELFSVWGAP-FLKEGASEEEINLSKMVMKFWANFAR 503

  Fly   483 TSDPNAPLTKSLVDW 497
            ..:||.   :.|..|
Mouse   504 NGNPNG---EGLPHW 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	156/535 (29%)
Ces1g	NP_067431.2	COesterase	23..545	CDD:395084	156/535 (29%)