Protein Alignment alpha-Est4 and Bche

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_011238302.1
• Gene: Bche / 12038
• MGIID: 894278
• Length: 615
• Species: Mus musculus
• Alignment Length: 587
• Identity: 170/587 - (28%)
• Similarity: 266/587 - (45%)
• Gaps: 105/587 - (17%)

  Fly     5 YNEDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPL 69
            :.|:..::.|..|:|||:.:..| .....||.|||||.||||:||||:|..|..|..|.:.::..
Mouse    40 HTEEDFIITTKTGRVRGLSMPVL-GGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDIHNATQYA 103

  Fly    70 SKCLQ-VSTLTKEVEG----------SEDCLYLNISVKTLNGDPMP------VMVYIHGGAFKGG 117
            :.|.| :.......:|          ||||||||:.:      |:|      |||:|:||.|:.|
Mouse   104 NSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWI------PVPKPKNATVMVWIYGGGFQTG 162

  Fly   118 DSSRRAWGPDYFMK-ENVVYISIGHRLGPLGFLSL-NDPDLEVPGNAGLKDVILALRWIRANAAN 180
            .||...:...:..: |.|:.:|:.:|:|.||||:. .:||  .|||.||.|..|||:|::.|.|.
Mouse   163 TSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPD--APGNMGLFDQQLALQWVQRNIAA 225

  Fly   181 FNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQME------YRLAKH 239
            |.|:|:.|||||.|:|:.:|.|.|..|||..||.||||.:|.|.....:...|      ..|||.
Mouse   226 FGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKF 290

  Fly   240 LGYEGDNVDSQVLEFLLKADPALIVSAD-FFTPLEKRQGHNMPFKPSIES---YSTPNAVLLAEP 300
            .|...:| :.::::.|...||..|:..: |..|.:.....|  |.|:::.   ...|:.:|....
Mouse   291 TGCSKEN-EMEMIKCLRSKDPQEILRNERFVLPSDSILSIN--FGPTVDGDFLTDMPHTLLQLGK 352

  Fly   301 IDLQRTTWSNRIPIILGANSGEGMSIF-----SFVKMNPSWL--KEFQCNPERVLPWTLRNRCDP 358
            :        .:..|::|.|..||.:..     .|.|.|.|.:  ||||   |.:      |...|
Mouse   353 V--------KKAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRKEFQ---EGL------NMYFP 400

  Fly   359 GQRRQLGQALIHHFCEAHGHELTVDHTNGLVEL------------FTHGFVHAMDRLIQSRLTYG 411
            |..|...:|::.::.:..|.:....:.:.|.::            ||..|....:.
Mouse   401 GVSRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTKKFAELENN--------- 456

  Fly   412 QAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAM 476
               .:.|.|:..|.       :....|..||.|..|:.::|.||...:::.:|.|....|.::..
Mouse   457 ---AFFYFFEHRSS-------KLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKT 511

  Fly   477 FVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFI------PQPEMPKLKFFDRLYEM 535
            :..||....||.....|.: | ||....::..|.::.|...|      ||.:..:| ||.::.||
Mouse   512 WANFAKYGHPNGTQGNSTM-W-PVFTSTEQKYLTLNTEKSKIYSKLRAPQCQFWRL-FFPKVLEM 573

  Fly   536 AG 537
            .|
Mouse   574 TG 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	165/575 (29%)
		Aes	<104..>219	CDD:223730	55/122 (45%)
Bche	XP_011238302.1	COesterase	46..563	CDD:365897	163/566 (29%)
		AChE_tetra	578..612	CDD:370053

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860