Protein Alignment alpha-Est4 and clt

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 185/549 - (33%)
• Similarity: 292/549 - (53%)
• Gaps: 49/549 - (8%)

  Fly    10 PVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIR-DCSKPLSKCL 73
            ||.|   |.:.|...|.:...::.:|.|:|||.||:|.|||:.|..|:.:.... ||||..:...
  Fly    23 PVKQ---GVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSY 84

  Fly    74 QVSTLTKEVEGSEDCLYLNI---SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVV 135
            |....|.||.||||||:||:   .||:.. .|:||||:||||.|..|:.:.....|...|::.|:
  Fly    85 QRDPFTLEVAGSEDCLFLNVYAPKVKSTR-TPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVI 148

  Fly   136 YISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTV 200
            .:::.:|||.||||||  |:..:.||.||||..|||.|::.|.|:|||||..:|:||.|:|..:|
  Fly   149 VVTLNYRLGALGFLSL--PEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSV 211

  Fly   201 QLLLASPQSEGLFHRAILLAG-FSME---LNRLPQMEYRLAKHLG---YEGDNVDSQVLEFLL-- 256
            .|...:..::.|||:||:.:| .:||   .|..|....|||:.||   :.||:  ..:|.||.
  Fly   212 HLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDS--KALLTFLQSE 274

  Fly   257 KADPALIV--SADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDL-QRTTWSNRIPIILGA 318
            ||.|..|:  :....:|.|:|:.....|||.:|..|:|:..|..:.::| .:......:|:|:|.
  Fly   275 KATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGY 339

  Fly   319 NSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNR-CDP-GQRRQLGQALIHHFCEAHGHELT 381
            ||.||::|....|..   |:.::.:..|::|   ||. .|| ....|...:.|..|. .:|..|:
  Fly   340 NSAEGLAIVVKAKQK---LEAYEDDLARLVP---RNLVLDPQAPEAQEAASDIRAFF-FNGQALS 397

  Fly   382 VDHTNGLVELFT-HGFVHAMDRLIQSRLT-YGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGH 444
            .::.:.||:||: :.|...:.|.::...: ..|:|.|.||.|:.. ..|.|:..|..::.|||.|
  Fly   398 KENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVG-GRNLYKKIFQNEDLRGVAH 461

  Fly   445 VDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTR--FGKRM 507
            .|::.|:|:: |..:.:.:|.:.....||..|:..||....| :|:      ||||.:  .|:.:
  Fly   462 ADDICYLFQM-AGDETEMNRDDLMVTERLCEMWANFARDGKP-SPI------WKPVKKPHNGEPI 518

  Fly   508 VLN---ISEELKFIPQPEMPKLKFFDRLY 533
            .|:   |..|||....|:..::.|:..:|
  Fly   519 QLDCLLIDRELKMCSNPDGERMDFWRSMY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	183/543 (34%)
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	183/543 (34%)