Protein Alignment alpha-Est4 and Ces2

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 154/519 - (29%)
• Similarity: 236/519 - (45%)
• Gaps: 76/519 - (14%)

  Fly     4 DYNEDAPVVQTTH-GKVRGILLKSLYDEQ--FYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDC 65
            |..|.:| ::||| |:|:| .|..:.|.:  .:.|.|||:|.||:|.|||..|...:||.|:||.
  Rat    28 DSPESSP-IRTTHTGQVQG-KLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEPPEPWSGVRDA 90

  Fly    66 SKPLSKCLQ------------VSTLTKEVEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKG 116
            :...:.|||            :..:...:..||||||||:  ......|..:||||:|||||...
  Rat    91 TSQPAMCLQNLDILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNLPVMVWIHGGALVV 155

  Fly   117 GDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANF 181
            |.:|... |....:.|::|.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|.|:|
  Rat   156 GMASMYD-GSLLTVNEDLVVVTIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWVQQNIAHF 217

  Fly   182 NGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQM--------EYRLAK 238
            .|:|.|:||||.|:|..:|...:.||.|:||||.||:.:|.::    ||.:        ...:||
  Rat   218 GGNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVAL----LPDLISETSETVSTTVAK 278

  Fly   239 HLGYEGDNVDSQVLEFLLKADPA---LIVSADFFTPLEKRQGHNMPFK--PSIESYSTPNAVLLA 298
            ..|.|.  :||:.|...|:|...   |::              |..||  |::    .....|..
  Rat   279 LSGCEA--MDSEALVRCLRAKSGAEILVI--------------NKVFKMIPAV----VDGEFLPR 323

  Fly   299 EPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEF-QCNPERVLPWTLRNRCDPGQRR 362
            .|.:|..:...:.:|.|:|.|:.|.......|......:||. :.|.:.||..|......|   .
  Rat   324 HPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLP---P 385

  Fly   363 QLGQALIHHFC--EAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSP 425
            :.|..|:..:.  ......|.:.:|..:.:     |:..:..|..:......||.|.|.|. .:|
  Rat   386 ECGDLLMEEYMGNTDDSQTLQIQYTEMMGD-----FLFVIPALQVAHFQRSHAPVYFYEFQ-HAP 444

  Fly   426 DFNFYRIRFMGKEQRGVGHVDELGYIF-KLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNA 488
            .: |..:|   .......|.||:.::| ...:..|||.:..|....||::..:..||...:||:
  Rat   445 SY-FKNVR---PPHVKADHADEVPFVFGSFFSGMKLDFTEEERLLSRRMMKYWANFARQGNPNS 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	152/515 (30%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	152/515 (30%)