Protein Alignment alpha-Est4 and nlgn3

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 177/638 - (27%)
• Similarity: 250/638 - (39%)
• Gaps: 184/638 - (28%)

  Fly    12 VQTTHGKVRGILLKSLYDEQFYAFD---GIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            |.|.:||:||..: .|..|.....|   |:|||.||:|..||..|.....|.|||:.:.....|.
 Frog    38 VNTHYGKLRGTRV-PLPSEILGPVDQYLGVPYAAPPVGEKRFLPPEPPPSWSGIRNATHFSPVCP 101

  Fly    74 Q------------------VSTLTKEV-EGSEDCLYLNISVKT-------------------LNG 100
            |                  :.|:|..: |.|||||||||.|.|                   ..|
 Frog   102 QNIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISKECVRKPNKKICRKG 166

  Fly   101 DP-------------------------MPVMVYIHGGAFKGGD------SSRRAWGPDYFMKENV 134
            .|                         .|||||||||::..|.      |...::|       ||
 Frog   167 GPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIHGGSYMEGSGNMIDGSVLASYG-------NV 224

  Fly   135 VYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMT 199
            |.|::.:|:|.|||||..|.  ...||.||.|.|.||||:..|.|.|.|||.|||:||...|:..
 Frog   225 VVITLNYRVGVLGFLSTGDQ--AAKGNYGLLDQIQALRWVSENVAFFGGDPHRITVFGSGIGASC 287

  Fly   200 VQLLLASPQSEGLFHRAILLAGFSME---LNRLPQMEYR-LAKHLGYEG-DNVDSQVLEFLLKAD 259
            |.||..|..|||||.|||:.:|.::.   :|..|....| ||:.:|... |.||  :::.|.:..
 Frog   288 VSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDTVD--MVDCLRQKS 350

  Fly   260 PALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGM 324
            ...:|..|.     :...:::.|.|.|:....|:     :|..|..........|:||.|.|||:
 Frog   351 AKELVEQDI-----QPARYHVAFGPVIDGDVIPD-----DPEILMEQGEFLNYDIMLGVNQGEGL 405

  Fly   325 ---------------SIFSFVKMNPSWLKEFQCNPE--RVLPWTLR-------NRCDPGQRRQLG 365
                           |.|.:...|  ::......||  ..|..|::       :|.:|..||:.
 Frog   406 KFVENVVDAEDGVSGSDFDYSVSN--FVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKT- 467

  Fly   366 QALIHHFCEAHGHELTVDHTNGLVELFT-HGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNF 429
                                  ||.||| |.:|............|| :|||.|.|        :
 Frog   468 ----------------------LVALFTDHQWVEPSVVTADLHARYG-SPTYFYAF--------Y 501

  Fly   430 YRIRFMGKEQ-RGVGHVDELGYIFKLPAT-----FKLDKSRPEFTAIRRLVAMFVQFAATSDPNA 488
            :..:.:.|.. ....|.||:.|:|.:|..     |..:.|:.:......::..:..||.|.|||.
 Frog   502 HHCQSLMKPAWADAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNK 566

  Fly   489 PLTKSLVDWKPVTRFGKRMVLNISEEL---KFIPQPEMPKLKFFDRLYEMAGV 538
            |:.:.       |:| .....|..||:   |:.|:         |:||...|:
 Frog   567 PVPQD-------TKF-IHTKANRFEEVAWSKYNPR---------DQLYLHIGL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	173/627 (28%)
nlgn3	XP_012823589.1	COesterase	35..618	CDD:395084	177/638 (28%)