Protein Alignment alpha-Est4 and nlgn1

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 661
• Identity: 182/661 - (27%)
• Similarity: 259/661 - (39%)
• Gaps: 210/661 - (31%)

  Fly     3 DDYNEDAPVVQTTHGKVRGILLKSLYDE---QFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRD 64
            ||.:   |||.||:||||| ..|.|.:|   ....|.|:|||.||:|..||:.|.....|..|::
 Frog    49 DDVD---PVVLTTYGKVRG-FKKELNNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKN 109

  Fly    65 CSKPLSKCLQ--VSTLTKEV------------------EGSEDCLYLNISVKTL----------- 98
            .::....|.|  |.....||                  :.|||||||||.|.|.
 Frog   110 STQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECAR 174

  Fly    99 ----------------------------------NGDPMPVMVYIHGGAFKGG-----DSSRRA- 123
                                              :|.|.|||||||||::..|     |.|..|
 Frog   175 KPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLAS 239

  Fly   124 WGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERI 188
            :|       ||:.|::.:|||.|||||..|...:  ||.||.|:|.||||...|...|.|||.||
 Frog   240 YG-------NVIVITVNYRLGVLGFLSTGDQASK--GNYGLLDLIQALRWTSENIGFFGGDPLRI 295

  Fly   189 TIFGHSSGSMTVQLLLASPQSE---------GLFHRAILLAGFSMELNRLPQMEYRLAKHLGYE- 243
            |:||..:|:..|.||..|..||         |||.|||..:|.::....:.....:.|:.|..:
 Frog   296 TVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKV 360

  Fly   244 GDNV-DS-QVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRT 306
            |.|: || :::|.|.|.....:|..| ..|:.    :::.|.|.|:....|:     :|..|...
 Frog   361 GCNMSDSGELVECLQKKPYRELVDQD-IQPVR----YHIAFGPVIDGDVIPD-----DPQVLMEQ 415

  Fly   307 TWSNRIPIILGANSGEGM---------------SIFSFVKMNPSWLKEFQCN------PERVLPW 350
            .......|:||.|.|||:               |.|.|...|      |..|      .:.:|..
 Frog   416 GEFLNYDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSN------FVDNLYGYTEGKDILRE 474

  Fly   351 TLR-------NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-HGFVHAMDRLIQSR 407
            |::       :|.:|..||:.                       |:.||| |.:|..........
 Frog   475 TIKFMYTDWADRNNPETRRKT-----------------------LLALFTDHQWVAPAVATADLH 516

  Fly   408 LTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQ----RGVGHVDELGYIFKLP-----ATFKLDKS 463
            ..:| :|||.|.|        ::..:   .:|    ....|.||:.|:|.:|     ..|..:.|
 Frog   517 SNFG-SPTYFYAF--------YHHCQ---TDQVPAWADASHGDEIPYVFGIPMIGPTELFPCNFS 569

  Fly   464 RPEFTAIRRLVAMFVQFAATSDPNAPL---TKSL---------VDWKPVTRFGKRMVLNISEELK 516
            :.:......::..:..||.|.|||.|:   ||.:         |.|   ||:.::..|.:...||
 Frog   570 KNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW---TRYSQKDQLYLHIGLK 631

  Fly   517 FIPQPEMPKLK 527
                   |::|
 Frog   632 -------PRVK 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	180/656 (27%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	180/658 (27%)