Protein Alignment alpha-Est4 and nlgn4xb

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 607
• Identity: 174/607 - (28%)
• Similarity: 256/607 - (42%)
• Gaps: 160/607 - (26%)

  Fly    12 VQTTHGKVRGILLKSLYD-----EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSK 71
            |.|.:||:||:.:....:     |||.   |:|||:.|.|..||:.|.....|.|||:.::....
Zfish    25 VTTNYGKLRGLRVALPSEILGPVEQFL---GVPYAMAPTGERRFQAPEPPLSWPGIRNATQFAPV 86

  Fly    72 CLQ-------------------VSTLTKEV-EGSEDCLYLNISVKTL-----NGDPMPVMVYIHG 111
            |.|                   :.|:...| :.|||||||||.|.|.     :....||||||||
Zfish    87 CPQFLEDRLLLTDMLPVWFTANLDTVATYVHDQSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHG 151

  Fly   112 GAFKGG-----DSSRRA-WGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILA 170
            |::..|     |.|..| :|       ||:.:::.:|||.|||||..|.  ...||.||.|.|.|
Zfish   152 GSYVEGTGNMIDGSVLASYG-------NVIVVTVNYRLGVLGFLSTGDQ--AAKGNYGLLDQIQA 207

  Fly   171 LRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSME---LNRLPQM 232
            |||::.|..:|:|||||:||||..:|:..|.||..|..||.||.:||:.:|.::.   :|..|..
Zfish   208 LRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIHSGTALSSWAVNYQPAK 272

  Fly   233 EYR-LAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVL 296
            ..| ||:.:|...|:. .:::|.|...:...::..: .||.:    :::.|.|.|:....|:
Zfish   273 YTRLLAEKVGCNEDDT-LELIECLQSKNYKELIEQN-ITPAK----YHIAFGPVIDGDVIPD--- 328

  Fly   297 LAEPIDLQRTTWSNRIPIILGANSGEGMSI---------------FSFVKMNPSWLKEFQCN--- 343
              :|..|..........|:||.|.|||...               |.|.      :.||..:
Zfish   329 --DPQILMEQGEFLNYDIMLGVNQGEGYKFVDGILDSEDRVTSNDFEFA------ISEFVDHLYG 385

  Fly   344 -PE--RVLPWTLR-------NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-HGFV 397
             ||  ..|..|::       :|.:|..||:.                       ||.||| |.:|
Zfish   386 YPEGKDTLRETIKFMYTDWADRENPEMRRKT-----------------------LVALFTDHQWV 427

  Fly   398 HAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRF-MGKEQRGVGHVDELGYIFKLPA----- 456
            ............|| :|||.|.|        ::..:. |........|.|||.|:|.:|.
Zfish   428 APAVATADLHAQYG-SPTYFYAF--------YHHCQSDMKPAWADSSHGDELPYVFGIPMIGPTD 483

  Fly   457 TFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTK--SLVDWKPVTRFGKRMVLNISEEL---K 516
            .|..:.|:.:......::..:..||.|.|||.|:.:  ..:..|| .||         ||:   |
Zfish   484 LFNCNFSKNDIMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP-NRF---------EEVAWSK 538

  Fly   517 FIPQPEMPKLKFFDRLYEMAGV 538
            :.|:         |:||...|:
Zfish   539 YNPK---------DQLYLHIGL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	170/596 (29%)
		Aes	<104..>219	CDD:223730	57/120 (48%)
nlgn4xb	NP_001159809.1	COesterase	17..567	CDD:278561	174/607 (29%)
		Aes	70..>243	CDD:223730	69/181 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840