Protein Alignment alpha-Est4 and cel.2

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001120027.1
• Gene: cel.2 / 100144991
• XenbaseID: XB-GENE-1217488
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 151/583 - (25%)
• Similarity: 234/583 - (40%)
• Gaps: 120/583 - (20%)

  Fly    11 VVQTTHGKVRGILLK--SLYDEQFYAFDGIPYAVPP------------LGTLRFKEPHDLKPWHG 61
            ||.|..|.|.|...|  .::.:....|.|||:|.||            .|||:.|   |.||
 Frog    24 VVHTEGGFVEGTNKKIGVVFPDYIDIFKGIPFAAPPKPFEKAEKHPGWSGTLQAK---DYKP--- 82

  Fly    62 IRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISV---KTLNGDPMPVMVYIHGGAFKGGDSSRRA 123
                     :|||.:.....|.||.||||||:.|   ::.....:||||:|.||.|..|......
 Frog    83 ---------RCLQATITQDNVFGSLDCLYLNVWVPQTRSQVSTNLPVMVWIFGGGFLLGSGQGAN 138

  Fly   124 W-------GPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANF 181
            :       |.:..|:..|:.::..:|:|||||||..|.:  .|||.||.|..:|:.|::.|.|.|
 Frog   139 FLSNYLYDGEEVAMRGKVIVVTFNYRVGPLGFLSTGDSN--APGNYGLWDQHMAIAWVKRNIAAF 201

  Fly   182 NGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSM---ELNRLP-QMEYRLAKHLGY 242
            .|||..||:||.|:|..:|.|...:|.:.||..|||..:|..:   .:.|.| .....||..||.
 Frog   202 GGDPNNITLFGESAGGASVSLQTLTPYNVGLIKRAISQSGVGLCPWAIQRDPLTWAKSLASKLGC 266

  Fly   243 EGDNVDSQVLEFLLKADPALIVSA---DFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQ 304
            ..:|. .::.:.|...||..:..|   ..|. ||....|.:.:.|.|:....|:     ||
 Frog   267 PVNNT-KELADCLRNTDPGALTIAYQLQLFN-LEYPLVHYLAYSPVIDGDFIPD-----EP---- 320

  Fly   305 RTTWSNR--IPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQA 367
            |..:||.  :..|.|.|:.:| .:|:.|.:........:.:.|:|                  |.
 Frog   321 RNLFSNAAGVDYIAGVNNMDG-HLFAGVDLPAINQPLHKISTEQV------------------QK 366

  Fly   368 LIHHFCEAHGHELTVDHTNGLVELFTHGF-----------------------VHAMDRLIQSRLT 409
            ::.....|.|    |...:...:|:|.|:                       |...:.|......
 Frog   367 VVRGLTLAKG----VPALDIAYDLYTAGWGTNPSQEDMKRTVVEVETDYIFLVATQEALALHYQN 427

  Fly   410 YGQAPTYLYRFDFDS--PDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRR 472
            ...|.||.|.|...|  |.:..:         .|..|.::|.::|..|.:..|.....:....:.
 Frog   428 AKGAKTYSYMFSHPSRMPVYPSW---------MGADHAEDLQFMFGKPFSTPLAYRPRDRDVAQY 483

  Fly   473 LVAMFVQFAATSDPNAPLTKSLVDWKPV-TRFGKRMVLNISEELKFIPQP-EMPKLKFFDRLY 533
            ::|.:..||||.||:...:.....|... |..|:.:.:|.....:.:.|. ..|.::|:.:.:
 Frog   484 MIAYWTNFAATGDPSKGESSIPTPWLAYSTENGQYLEINHKINYQSMKQSLRSPYVRFWAQTF 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	150/577 (26%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:395084	150/577 (26%)