Protein Alignment alpha-Est4 and ces2

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 157/585 - (26%)
• Similarity: 241/585 - (41%)
• Gaps: 159/585 - (27%)

  Fly     7 EDA-PVVQTTHGKVRGILLKSL----YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCS 66
            ||| |::.|.:|::.|   |::    .|...:.|.|:|:|.||:|.|||:.|...:||..:|:.:
 Frog    21 EDARPLLMTKYGQLLG---KTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSVREAT 82

  Fly    67 KPLSKCLQVSTLTKEV---------------EGSEDCLYLNISVKTLNGD--PMPVMVYIHGGAF 114
            .|...|||    .|||               ..||||||||:......|:  .:||||:||||..
 Frog    83 APSPMCLQ----DKEVMELLADFFKAKFDFSRVSEDCLYLNVFTPADKGENPGLPVMVFIHGGGL 143

  Fly   115 KGGDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAA 179
            ..|.:|... |......||||.:||.:|||.:||||..|.  ||.||.|..|.:.||:|:|.|..
 Frog   144 AIGGASMFE-GSALSAYENVVVVSIQYRLGIMGFLSTGDK--EVRGNFGFLDQVAALQWVRDNIK 205

  Fly   180 NFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAI------LLAGFSMELNR--LPQMEY-- 234
            :|.|||:.:||||.|:|.::|..|:.||.|||||||||      :|.|.:.....  ||.::.
 Frog   206 DFGGDPQSVTIFGESAGGLSVSALVLSPLSEGLFHRAIAESGVAILPGLTASKTEEILPLLDMVI 270

  Fly   235 -----RLAKHLGYEGDNVDSQVLEFLLKAD----PALIVSADFFTPLEK----RQGHNMPFKPSI 286
                 .::..:|...:..:.:::|......    ||::.......|.|:    ::.|.:||...|
 Frog   271 NVSSCSVSDLVGCLKNKTEDEIIEITAAMRYVIFPAVVDGVFLPKPAEEILAAKESHPVPFLIGI 335

  Fly   287 ESYSTPNAVLLAEPIDLQRTTW-----SNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPER 346
            .::...:.:    |:.|..|.:     ...|..||||     :.:.:.|              ..
 Frog   336 NNHEFGSML----PVTLNITGYREGMEKKDIQAILGA-----LPLLNTV--------------SS 377

  Fly   347 VLPWTLR----NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT------HGFVHAMD 401
            |:|:.:.    :..||.:.|       ::|.:..|..:.|     :..|.|      .||
 Frog   378 VIPFIMEEYFGDTNDPKELR-------NNFLDLAGDIIFV-----IPALRTAKYHRDSGF----- 425

  Fly   402 RLIQSRLTYGQAPTYLYRF------------DFDSPDFNFYRIRFMGKEQRGVGHVDEL-----G 449
                        |.|.|.|            ||...|                 |.|||     |
 Frog   426 ------------PVYFYEFQHRPSLYADSKEDFVKAD-----------------HGDELYFVGGG 461

  Fly   450 YIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEE 514
            ...|....||.:.:..|....:.::..:..||...|||.   ..|.:|.........:.:|::::
 Frog   462 PFLKNGILFKSNGTEEEKILSKTIMKYWANFARNGDPNG---HGLAEWPKYDEDEDYLEINLTQK 523

  Fly   515  514
             Frog   524  523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	156/584 (27%)
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	154/581 (27%)