Protein Alignment alpha-Est4 and Ces1f

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001096829.2
• Gene: Ces1f / 100125372
• RGDID: 1642419
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 168/599 - (28%)
• Similarity: 251/599 - (41%)
• Gaps: 143/599 - (23%)

  Fly    10 PVVQTTHGKVRG--ILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRD-------C 65
            |||.||.|||.|  :.|:.: .:....|.|:|:|.||||:|||..|...:||..:::       |
  Rat    24 PVVDTTKGKVLGKYVSLEGV-TQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMC 87

  Fly    66 SKPLSKCLQVSTL---TKE---VEGSEDCLYLNISVKT--LNGDPMPVMVYIHGGAFKGGDSSRR 122
            |:..:|..:::.|   .||   :|.|||||||||....  .....:||||:||||....|.:|..
  Rat    88 SQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGASTY 152

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            . |......||||.::|.:|||..||.|..|....  ||.|..|.:.||.|::.|.|||.|||..
  Rat   153 D-GRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSR--GNWGHLDQVAALHWVQDNIANFGGDPGS 214

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQM--------EYRLAKHLGYE- 243
            :||||.|:|..:|.:|:.||.::.||||||..:|...    ||.:        ..::|...|.|
  Rat   215 VTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVF----LPGLLTKDVRPAAKQIADMAGCET 275

  Fly   244 ----------GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYST--PNAVL 296
                      ....:.::||.:.|.:...:.|          |..|   |.|....||  .|.||
  Rat   276 TTSAIIVHCLRQKTEEELLEIMKKMNLIKLSS----------QRDN---KESYHFLSTVVDNVVL 327

  Fly   297 LAEPIDLQRTTWSNRIPIILGANSGE-GM---SIFSFV--------KMNPSWLKEFQC---NPER 346
            ..:|.::......|.:|.|:|.|..| |.   ::..||        ||..:.|::|..   .||.
  Rat   328 PKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPED 392

  Fly   347 VLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTY- 410
            ::|..:..     .|:              |.:.::...:|::     .|:..:...|.|.:..
  Rat   393 IIPVAIEK-----YRK--------------GSDDSIKIRDGIL-----AFIGDVSFSIPSVMVSR 433

  Fly   411 ----GQAPTYLYRF----DFDSPDFNFYRIRFMGKEQRGVG-HVDELGYIFKLPATFKLDKSRPE 466
                ..||||:|.:    .|.||.          :.:..|| |.|:|..:|..| ..:...|..|
  Rat   434 DHRDAGAPTYMYEYQYYPSFSSPQ----------RPKHVVGDHADDLYSVFGAP-ILRDGASEEE 487

  Fly   467 FTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNI-----------SEELKF--- 517
            ....:.::..:..||...:||.   :.|..|....:  |...|.|           :||:.|
  Rat   488 IKLSKMVMKFWANFARNGNPNG---RGLPHWPQYDQ--KEEYLQIGATTQQSQRLKAEEVAFWTQ 547

  Fly   518 -----IPQPEMPKL 526
                 .|||...:|
  Rat   548 LLAKRQPQPHHNEL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	168/599 (28%)
Ces1f	NP_001096829.2	COesterase	22..545	CDD:395084	163/581 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561		0/2 (0%)