Protein Alignment alpha-Est4 and nlgn1

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 660
• Identity: 182/660 - (27%)
• Similarity: 261/660 - (39%)
• Gaps: 203/660 - (30%)

  Fly     2 SDDYNEDAPVVQTTHGKVRGILLKSLYDE---QFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIR 63
            |:..:|..|:|.||:||||| ..|.|.:|   ....|.|:|||.||.|..||:.|.....|..||
Zfish    46 SEKLDETDPIVTTTYGKVRG-FKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIR 109

  Fly    64 DCSKPLSKCLQVSTL--------------TKEVE--------GSEDCLYLNISVKT--------- 97
            :.::....|.|  ||              |..:|        .|||||:|||.|.|
Zfish   110 NATQFAPVCPQ--TLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKE 172

  Fly    98 ------------------------------------LNGDPMPVMVYIHGGAFKGG-----DSSR 121
                                                .:|.|.||||::|||::..|     |.|.
Zfish   173 CARKPGKKICRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEGTGNMFDGSI 237

  Fly   122 RA-WGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDP 185
            .| :|       ||:.|::.:|||.|||||..|.  ...||.||.|:|.||||...|.|.|.|||
Zfish   238 LASYG-------NVIVITVNYRLGVLGFLSTGDQ--AAKGNYGLLDLIQALRWTSENIAFFGGDP 293

  Fly   186 ERITIFGHSSGSMTVQLLLASPQSE---------GLFHRAILLAGFSME---LNRLPQMEYR-LA 237
            .|||:||..:|:..|.||..|..||         |||.|||..:|.::.   ::..|....| ||
Zfish   294 LRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLA 358

  Fly   238 KHLGYE-GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPI 301
            |.:|.. .|.|  :::|.|.|.....:|..|.     :...:::.|.|.|:....|:     :|.
Zfish   359 KKVGCNLKDTV--EMVECLQKKHYKELVEQDI-----QPARYHIAFGPVIDGDVIPD-----DPQ 411

  Fly   302 DLQRTTWSNRIPIILGANSGEGMSIFSFVKMN-------------PSWLKEFQCNPE--RVLPWT 351
            .|..........|:||.|.|||:.....:..|             .|::.:....||  .:|..|
Zfish   412 ILMEQGEFLNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRET 476

  Fly   352 LR-------NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-HGFVHAMDRLIQSRL 408
            ::       :|.:|..||:.                       |:.||| |.:|...........
Zfish   477 IKFMYTDWADRHNPETRRKT-----------------------LLALFTDHQWVAPAVATADLHS 518

  Fly   409 TYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQ----RGVGHVDELGYIFKLP-----ATFKLDKSR 464
            ::| :|||.|.|        ::..:   .||    ....|.||:.|:|.||     ..|..:.|:
Zfish   519 SFG-SPTYFYAF--------YHHCQ---TEQVPPWADAAHGDEIPYVFGLPMIGPTELFPCNFSK 571

  Fly   465 PEFTAIRRLVAMFVQFAATSDPNAPL---TKSL---------VDWKPVTRFGKRMVLNISEELKF 517
            .:......::..:..||.|.|||.|:   ||.:         |.|   ||:.::..|.:...||
Zfish   572 NDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW---TRYNQKDQLYLHIGLK- 632

  Fly   518 IPQPEMPKLK 527
                  |::|
Zfish   633 ------PRVK 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	181/655 (28%)
		Aes	<104..>219	CDD:223730	58/129 (45%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	180/653 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740