Protein Alignment alpha-Est4 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 578
• Identity: 171/578 - (29%)
• Similarity: 255/578 - (44%)
• Gaps: 138/578 - (23%)

  Fly    10 PVVQTTHGKVRGILLKSLYD------EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKP 68
            |:|.|.:||:||: .|.|.:      ||:.   |:|||.||:|..||:.|.....|..||:.::.
Zfish    52 PMVTTGYGKLRGV-RKELNNEILGPVEQYL---GVPYATPPVGERRFQPPEAPGSWQEIRNATQF 112

  Fly    69 LSKCLQ-VSTLTKEV------------------EGSEDCLYLNISVKTLNGDPM----------- 103
            ...|.| :..:..|:                  ..||||||||:.|.|.:| |:
Zfish   113 APVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDG-PLTKKHDESSMNR 176

  Fly   104 ------------PVMVYIHGGAFKGG-----DSS-RRAWGPDYFMKENVVYISIGHRLGPLGFLS 150
                        |||::||||:|..|     |:| ..|:|       ||:.:::.:|||.|||||
Zfish   177 PRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASVLAAYG-------NVIVVTMNYRLGVLGFLS 234

  Fly   151 LNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHR 215
            ..|...:  ||.||.|.|.||||:..|..:|.||||||||||..:|:..|.||:.|..|||||.|
Zfish   235 SGDQSAK--GNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQR 297

  Fly   216 AILLAG---FSMELNRLPQMEYR-LAKHLGYE-GDNVDSQVLEFLLKADPALIVSADFFTPLEKR 275
            ||..:|   .|..:|..|.|..: |||.:|.. .|..|  :::.|.:.....:|..|.     :.
Zfish   298 AIAQSGSAISSWSVNYRPLMYTKILAKKVGCSYSDTAD--LVDCLRRKSYRELVDQDV-----QP 355

  Fly   276 QGHNMPFKPSIESYSTPNAVLLAEP-IDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKE 339
            ..:::.|.|.::....|:     :| |.:|:..:.| ..|:||.|.|||:   .||..|.
Zfish   356 ARYHIAFGPVVDGDVVPD-----DPEILMQQGEFLN-YDILLGVNQGEGL---KFVDDNE----- 406

  Fly   340 FQCNPERV----LPWTLRNRCD-----PGQRRQLGQALIHHFCEAHGHELTVDHTNG------LV 389
               ..|.:    ..:|:.|..|     |..:..|.:.:...:.:      ..|..||      |:
Zfish   407 ---GEEGISAASFDYTISNFVDNLYGYPEGKDILRETIKFMYTD------WADRDNGDMRRKTLL 462

  Fly   390 ELFT-HGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGK-EQRGVGHVDELGYIF 452
            .||| |.:|.......:....: |:|.|.|.|        .:..:...: |.....|.||:.|:|
Zfish   463 ALFTDHQWVAPAVATAKLHAEF-QSPVYFYTF--------HHHCQTEARPEWADAAHGDEIPYVF 518

  Fly   453 KLP---AT--FKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTK--SLVDWKPVTRF 503
            .:|   ||  |..:.|:.:......::..:..||.|.|||.|:.:  ..:..|| .||
Zfish   519 GVPMVGATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKP-NRF 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	171/578 (30%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	171/578 (30%)