Protein Alignment alpha-Est5 and Ces1h

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 569
• Identity: 162/569 - (28%)
• Similarity: 247/569 - (43%)
• Gaps: 88/569 - (15%)

  Fly    18 GQIKGVKRLSL--YDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGLLT 80
            |::.| |.:||  :..|...|..:||||||||.|||..|.|.:|||.|.:.|.|....:|..:|.
Mouse    31 GKVLG-KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDAVLG 94

  Fly    81 REIEG-------------GEDCLYLNVYS--KQLKSEKPLPVMVYIYGGAFTVGEATRELY-GPD 129
            :.:..             .|||||||||:  ..:|:...|||||:|:||...||.|:  .| |..
Mouse    95 QMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGAS--AYDGRT 157

  Fly   130 YFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFG 194
            ....::||:||:.||:...||.|..|...:  ||.|..||:.||.|::..|:||.||..::|:||
Mouse   158 LSAHENVVVVTIQYRLAIWGFFSTGDEHSR--GNWGHLDQLAALHWIQDNIANFGGDPGSVTIFG 220

  Fly   195 ESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTG---------- 249
            :||||.|...::.:...:.|||:||..||.|  :.:....|| |..:.:|...|.
Mouse   221 QSAGGESVSVLVLSPLAKNLFHRAISQSGVV--FTSGLFMED-ASSVTEQIAVTAGCKTTTSAVI 282

  Fly   250 -----ENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLL-FAFGPTVEAYVGEDCVVPKPPVEM 308
                 :..:.::||.:|.:        ||...:.:.|... :.|.|||.    :..|:||.|..:
Mouse   283 VHCLRQKTEEELLEIMQKM--------NLFKLDAQENTKKNYPFLPTVL----DGVVLPKAPEAI 335

  Fly   309 ARDAWSNNFPVMLGGTSFEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEY---- 369
            ..:...|..|.::|....|..:..|.:          .:.|...|.:|.:.:|.....|.|
Mouse   336 LAEKNFNTVPYIVGINKQEFGWTLPMI----------MEFPPTDVKLDKKVISLFLRKLAYFFNI 390

  Fly   370 -SQRLMKAYFGYSPPSSELLLN---MLDFYSYKIFWHGFNRTFNAR-LTYAKAPTYYYRFDFDSP 429
             ...:..|...||..:.:.:.|   :|......:|  |......:| ...|.||||.|.|. ..|
Mouse   391 PEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMF--GIPSVIVSRGHRDAGAPTYMYEFQ-SRP 452

  Fly   430 NFNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMIGIWTAFAATSNPNCP 494
            :|    :.....|..|| .|.|::..:| .|...:...:..|....:.|:..|..||...|||..
Mouse   453 SF----SSELKPKTVTG-DHGDEVYSVF-GAPILREGSSEEEINLSKMMMKFWANFARNGNPNGQ 511

  Fly   495 EIGHLEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDNL--YKPNQ 541
            .:.|  |  ...|..|..:.|.:........:.:::.:|..|  .||.|
Mouse   512 GLPH--W--PEYNQKKGYLQIGATTQQAQGLKDKEVSLWTELRAKKPPQ 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	155/534 (29%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	157/557 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832589
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640