Protein Alignment alpha-Est5 and Nlg1

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 635
• Identity: 151/635 - (23%)
• Similarity: 245/635 - (38%)
• Gaps: 173/635 - (27%)

  Fly    10 TCELTLPVGQIKGVKR-------LSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCT 67
            |.|:.:..|::.|:.|       |...|    .|..:|:|:.|.|..||..|....||.|:....
  Fly   155 TQEIQVKQGRLMGITRRFQVTSGLRQVD----QFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIAR 215

  Fly    68 HYAEKPTQR---------------------GLLTREIEGGEDCLYLNVY---SKQLKSEKPLPVM 108
            |......|:                     .||.......|||||||:|   .:...:.|...|:
  Fly   216 HLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280

  Fly   109 VYIYGGAFTVGE------ATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVP--GNAG 165
            ||::|.:|....      :....||       :|::||:|||:..||||.   ||:...  .|..
  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYG-------EVIVVTVNYRLGVLGFLR---PSIDAHNIANYA 335

  Fly   166 LKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYW- 229
            |.||:.||.|:|:.|..|.||:|.:|:.|.|.|....:::|.:....||||:||.|||:..:.|
  Fly   336 LLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA 400

  Fly   230 ANNPAEDFAFRLAQQ-----NGFTGENDDAKVLEYLQGVPARDLVN-HNLLTPEHRRNGLLFAFG 288
            |:|.:.....::|..     |......||..:|:.|:....:|::: ...||.      ...:.|
  Fly   401 ASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQ------FSTSLG 459

  Fly   289 PTVEAYVGEDCVVPKPPVEMARDAWS--NNFPVMLGGTSFEGLFMYPAVSANLKALDSLSQDPTR 351
            |.|:.:     |:|..|.::......  :.:.::.|.|..|.   |..::| |...:.|.:
  Fly   460 PIVDGH-----VIPNQPYKVMGHYTEHFSRYDLLFGITESES---YHTLAA-LALEEGLRE---- 511

  Fly   352 LVPVDVRTVSSEKENLEYSQRLMKAYFGYSP--PSSELLLNMLDFYSYKIFWHGFNRTFNARLTY 414
                      :|::||  .:..|::.|...|  ..:..|....|.|:..|
  Fly   512 ----------NERDNL--LRFYMQSRFDIRPDLALAATLKKYQDMYNNPI--------------- 549

  Fly   415 AKAPTYYYR---FDFDSPNFNFYRAKFCGDKIKTGVAHAD------------------------- 451
             ||....:|   .|..|.      |:..|..::||:.|||
  Fly   550 -KATNLEHRDVVLDILSD------ARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHS 607

  Fly   452 ----DLSYLF----RNAGSWKLDKTSAEYRTI-ERMIGIWTAFAATSNPNCPEIG-----H-LEW 501
                :|:::|    ..||.:.....:.:.:.: |.::..||.|..|.||..|..|     | |||
  Fly   608 IMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEW 672

  Fly   502 K------PSTKNDPKRVINISSDVTIIDLPEYEKLQIWDNLYK---PNQL 542
            .      |......:..:||....|:    .|:..||:.|.:.   |::|
  Fly   673 DRYDLDWPEFNRRAQAYLNIGIPPTV----GYKYRQIYMNFWNKELPDEL 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	142/598 (24%)
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	149/625 (24%)
		Aes	<263..>408	CDD:223730	51/154 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810