Protein Alignment alpha-Est5 and Nlg3

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 174/695 - (25%)
• Similarity: 256/695 - (36%)
• Gaps: 229/695 - (32%)

  Fly    18 GQIKGV------KRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQR 76
            |.|.||      :.|    ||..::..||:|.||:|.|||..||.|..||||.....::....||
  Fly   163 GAISGVIVQLDGRHL----DPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQR 223

  Fly    77 --------GLLTREIEG---------------GEDCLYLNVY----------------------- 95
                    ..|.|..:|               .|||||||:|
  Fly   224 LPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSS 288

  Fly    96 ----------------SKQLKSEKP--LPVMVYIYGGAFTVGE------ATRELYGPDYFMTKDV 136
                            |....|..|  .||:|:::|.::....      :....||       .:
  Fly   289 SGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG-------QI 346

  Fly   137 VLVTLNYRVDCLGFLSLK-DPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGC 200
            ::||:|||:..||||:.. |...|:|.|.||.|.:.||.|:|:.|:.|.||.::||:.|...|..
  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411

  Fly   201 STHFMMCTEQT-RG-LFHKAIPMSGTVHNYWA--NNPAEDFAFRLAQQNGFTGENDDA------- 254
            ..||::.:... .| ||::||.|||:....|:  :|||: :|..:|.......:...|
  Fly   412 CVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK-YAAIVAHHVNCASDLPHAHLMKCLR 475

  Fly   255 -KVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYV--GEDCVVPKP--PVEMARDAWS 314
             |.|:.|..||.|        .||..     |||||:::..|  |.|.|.|.|  |...|:...|
  Fly   476 EKTLDQLLSVPIR--------PPEFG-----FAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQAS 527

  Fly   315 NNFPVMLGGTS-------------FEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKEN 366
            ......|||.:             .|.:.:....:.|..:...|....||....    .|....:
  Fly   528 TAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAF----FSFNSGD 588

  Fly   367 LEYS------QRLMKAYFGYSPPSSELLLNMLDFYSYKIF---------W-----HGFN---RTF 408
            ::|.      .|::|||          :.|...|:..:||         |     |..|   .|.
  Fly   589 VQYGIEADRRSRILKAY----------VRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETL 643

  Fly   409 NARLTYAK--AP--------------TYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLF 457
            .| |:.|:  ||              :|.|.||        |:.:|.....:.|..|.:||.|:|
  Fly   644 EA-LSDAQVVAPAAQTVDLHSADHRNSYLYVFD--------YQTRFGDYPQRQGCIHGEDLPYIF 699

  Fly   458 ------------RNAGSWKLDKTSAEYRTIERMIGIWTAFAATSNPN-CPEIGH----------- 498
                        ||       .|..|....|.::..|:.|..|.||| ..|..|
  Fly   700 GAPLVGGFNHFTRN-------YTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKT 757

  Fly   499 LEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDN----LYKP 539
            :|| .:.::..|:.:|..:...:.:.....:|..|.|    |:||
  Fly   758 IEW-TAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKP 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	166/660 (25%)
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	169/683 (25%)
		Aes	<313..>410	CDD:223730	34/103 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740