Protein Alignment alpha-Est5 and alpha-Est1

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 268/537 - (49%)
• Similarity: 353/537 - (65%)
• Gaps: 24/537 - (4%)

  Fly    18 GQIKGVKRLSLYDDP-YFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGLLTR 81
            ||::|.:|.:|||:. ||:||.||||:||:||||||||.|..||.||.|||:...||.|:..:..
  Fly    40 GQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTYPRAKPMQKHFVLS 104

  Fly    82 EIEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDYFMTKDVVLVTLNYRVD 146
            .:||.|||||||||||:|:|:|||||:|:||||.|..|||.|:.|.|||||.:|||:||.||||.
  Fly   105 IVEGSEDCLYLNVYSKRLRSDKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVG 169

  Fly   147 CLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQT 211
            .||||||.|..|.|||||||||||:||:|:.|.|:.||||..||||.|||||..|.|.:|.||||
  Fly   170 ALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQT 234

  Fly   212 RGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARDLVNH--NLL 274
            ||||||||..||::...|||.|:..:|:|||.|.|::|..::.:|..|||..||.::...  .|:
  Fly   235 RGLFHKAIMQSGSMFCEWANEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLV 299

  Fly   275 TPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPAVSAN- 338
            :.|.||..:||.|.|.||.|:..|||:|:...||..:||.|:.|::|||.||||||.|.:...:
  Fly   300 SQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGLFSYQSTLHDE 364

  Fly   339 ---LKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAY----FGYSPPSSELLLNMLDFYS 396
               |.|.:.       |:|.::|    ||....:.:.|::.:    |..:..........|...|
  Fly   365 EHMLSAFEV-------LIPREIR----EKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHILS 418

  Fly   397 YKIFWHGFNRTFNARLTYAKA-PTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNA 460
            .|.||||.:||..|||::|.| |||.||||.|||:||.:|...||..:: ||:|||||||||.:.
  Fly   419 VKHFWHGIHRTVLARLSHAPATPTYLYRFDVDSPHFNHFRQVMCGKHVR-GVSHADDLSYLFYHI 482

  Fly   461 GSWKLDKTSAEYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTIIDLP 525
            .:.|:||:|.||:||:|::|:|.|||...|||||:||...|:...:..|:..:||...:..|.||
  Fly   483 LANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQLEFIVLP 547

  Fly   526 EYEKLQIWDNLYKPNQL 542
            |.::.:|||.||..|.|
  Fly   548 ESKQNRIWDRLYDKNDL 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	254/503 (50%)
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	257/512 (50%)
		Aes	<117..>233	CDD:223730	77/115 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467361
Domainoid	1	1.000	450	1.000	Domainoid score	I1603
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2231
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26273
OrthoDB	1	1.010	-	-		D18817at7147
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	12	11.810