Protein Alignment alpha-Est5 and alpha-Est4

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 213/529 - (40%)
• Similarity: 327/529 - (61%)
• Gaps: 19/529 - (3%)

  Fly    18 GQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGLLTRE 82
            |:::|:...||||:.:::|:.||:|.||||.|||:.|....||.|:.||:....|..|...||:|
  Fly    17 GKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVSTLTKE 81

  Fly    83 IEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDYFMTKDVVLVTLNYRVDC 147
            :||.|||||||:..|.|..: |:||||||:||||..|:::|..:||||||.::||.:::.:|:..
  Fly    82 VEGSEDCLYLNISVKTLNGD-PMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVVYISIGHRLGP 145

  Fly   148 LGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTR 212
            ||||||.||.|:|||||||||.:|||:|::...:|||||...||:||.|:|..:...::.:.|:.
  Fly   146 LGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSE 210

  Fly   213 GLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARDLVNHNLLTPE 277
            ||||:||.::|.....   |......:|||:..|:.|:|.|::|||:|.......:|:.:..||.
  Fly   211 GLFHRAILLAGFSMEL---NRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPL 272

  Fly   278 HRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPAVSANLKAL 342
            .:|.|....|.|::|:|...:.|:...|:::.|..|||..|::||..|.||:.::..|..|...|
  Fly   273 EKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWL 337

  Fly   343 DSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAY---FGYSPPSSELLLN----MLDFYSYKIF 400
            .....:|.|::|..:|......:..:..|.|:..:   .|:     ||.::    :::.:::. |
  Fly   338 KEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGH-----ELTVDHTNGLVELFTHG-F 396

  Fly   401 WHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKL 465
            .|..:|...:||||.:||||.||||||||:|||||.:|.| |.:.||.|.|:|.|:|:...::||
  Fly   397 VHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMG-KEQRGVGHVDELGYIFKLPATFKL 460

  Fly   466 DKTSAEYRTIERMIGIWTAFAATSNPNCPEIGHL-EWKPSTKNDPKRVINISSDVTIIDLPEYEK 529
            ||:..|:..|.|::.::..|||||:||.|....| :|||.|:...:.|:|||.::..|..||..|
  Fly   461 DKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEMPK 525

  Fly   530 LQIWDNLYK 538
            |:.:|.||:
  Fly   526 LKFFDRLYE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	201/499 (40%)
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	210/522 (40%)
		Aes	<104..>219	CDD:223730	61/114 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467385
Domainoid	1	1.000	222	1.000	Domainoid score	I1478
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2231
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	10	9.900