Protein Alignment alpha-Est5 and CG12869

DIOPT Version :10

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 132/576 - (22%)
• Similarity: 225/576 - (39%)
• Gaps: 135/576 - (23%)

  Fly     2 MSKESSLETCELTLPVGQIKGVKRLSLYDD----PYFSFEKIPFAKPPLGELRFRAPVPADPWSG 62
            :|...|.:...:.|..|.:.|:|   ::.|    ..::|..||:|:.|:.||||....|:..::.
  Fly    20 LSPYISAQQTHIKLEQGDLIGLK---VFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNR 81

  Fly    63 VLDCTH------------YAEKPTQRGLLTREIEGGEDCLYLNVYSKQ--LKSEKPLPVMVYIYG 113
            .|..|.            |.|  :..|.:.|.:...|||||||:::.:  ::..| ||::|.:.|
  Fly    82 TLQATTMQPLCPQLANTIYDE--SSDGSMPRSVSTDEDCLYLNIWTPESGMRYGK-LPIVVIVTG 143

  Fly   114 GAFTVGEATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQ 178
            ..|........:.|.| ...:.:|:|::.||.:..|:|||.:....||||.||.|..:||:|:::
  Fly   144 EEFAYDWPRNRINGLD-LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRR 207

  Fly   179 YISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTV-------HNYWANNPAED 236
            ....|.|:..:||:.|..:||.....:...|.:..:....:...|.:       |..|.....:.
  Fly   208 NADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQV 272

  Fly   237 FAFRLAQQNGFTGENDDAKVLEYLQGVPARDLV-------NHNLLTPEHRRNGLLFAFGPTVEAY 294
            ...:|..|   ..|....:::..|:.....||:       ||.        ||         .:.
  Fly   273 LVQKLGCQ---FEEAQRRQLMGCLRRKSREDLLRAYESVYNHG--------NG---------SSQ 317

  Fly   295 VGEDCVVPKP-PVEMARDAWSNNFPVMLGGTSFEGLF-----------------------MYPAV 335
            :|  .::|:. |:|. |.......||:||.||.||.|                       :.|.|
  Fly   318 LG--VILPEGLPLEQ-RLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNV 379

  Fly   336 SANLKALDSLSQD-PTRLVPVDVRTVSSEKENLEY----SQRLMKAYFGYSPPSSEL--LLNMLD 393
               ::||:|:.:: .|:|..:..|..:.:.|.:.:    .|||:.... |..|.|.:  |||...
  Fly   380 ---MRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESL-YELPYSRILELLNGTT 440

  Fly   394 FYSYKIFWHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSY--- 455
            .|:| :|.|..:.....|                       |..|      .|.:|:.||..
  Fly   441 SYAY-VFDHSHSMDMRGR-----------------------RNLF------GGASHSSDLPLLLG 475

  Fly   456 --LFRNAGSWKLDKTSAEYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDP 509
              ||:.....:.  :..|.:...::.|.:..|....||....| :..|.|..|.:|
  Fly   476 PSLFQQIARRRF--SGEEEQLCRKIRGAFANFIKNGNPTPGRI-YDGWLPYNKENP 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	130/566 (23%)
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	130/569 (23%)