Protein Alignment alpha-Est5 and Ces1a

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 554
• Identity: 172/554 - (31%)
• Similarity: 237/554 - (42%)
• Gaps: 99/554 - (17%)

  Fly     6 SSLETC----ELTLP------VGQIKGVKRLSLYD--DPYFSFEKIPFAKPPLGELRFRAPVPAD 58
            :||.||    .|:.|      .|::.| |.:||..  .|...|..:||||||||.|||..|.||:
Mouse     9 ASLNTCMALGHLSSPPVVDTLQGKVMG-KYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAE 72

  Fly    59 PWSGVLDCTHYAEK--------PTQRGLLTREIEG-----GEDCLYLNVYS-KQLKSEKPLPVMV 109
            .||.|.:.|.|...        |....:.|.::|.     .|||||||:|| ..|.|:..|||||
Mouse    73 TWSSVKNTTSYPPMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMV 137

  Fly   110 YIYGGAFTVGEATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALK 174
            :::||....|.|: ...|......::||:|.:.||:...||||..|...:  ||.|..|||.||:
Mouse   138 WVHGGGLLSGGAS-TFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSR--GNWGHLDQVAALQ 199

  Fly   175 WVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPA--EDF 237
            ||:..|:||.||.|::|:|||||||.|...::.:..|:.||.:||..||.     |..|.  .:.
Mouse   200 WVQNNIANFGGDPSSVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGV-----ALTPCLFRET 259

  Fly   238 AFRLAQQNGF-TG--ENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAY----- 294
            ..|.|:|... ||  ....|.::..|:.....:|    |.|....:...|...|...|:|
Mouse   260 TRRAAEQVAIATGCVATTSADIVHCLREKTEEEL----LATTLKMKFFALDLLGDPRESYPFLTT 320

  Fly   295 VGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFE-GLFM-----YPAVSANL--KALDSL--SQDP 349
            |.:..|:||.|.|:..:...|..|.::|....| |.|:     ||.....|  |:..||  ...|
Mouse   321 VIDGVVLPKAPEEILAEKSFNTVPYIVGINKQEFGWFIPMMMGYPLSEGKLDQKSATSLLWKSYP 385

  Fly   350 TRLVPVDVRTVSSEKENLEYSQRLMKAYFGYS---PPSSELLLNMLD---FYSYKIFWHGFNRTF 408
            ...:..::..|::||            |.|.|   ....:|.|:|:.   |....:....::|.
Mouse   386 LTNISKELTPVATEK------------YLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRD- 437

  Fly   409 NARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGD-KIKTGVAHADDLSYLFRNAGSWKLDKTSAEY 472
                  |.||||.|.|.        |...|..| :.||.:|...|..|........|...:..|.
Mouse   438 ------AGAPTYMYEFK--------YHPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGASEEEI 488

  Fly   473 RTIERMIGIWTAFAATSNPN------CPEIGHLE 500
            .....|:..|..||...|||      .||.|..|
Mouse   489 NLSTMMMKFWGNFARNGNPNGEGLPHWPEYGEKE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	172/553 (31%)
Ces1a	NP_001013786.2	Esterase_lipase	25..536	CDD:238191	166/538 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650