Protein Alignment alpha-Est5 and Ces1c

DIOPT Version :10

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 168/578 - (29%)
• Similarity: 260/578 - (44%)
• Gaps: 88/578 - (15%)

  Fly     6 SSLETCEL-------TLPV-----GQIKGVKRLSL--YDDPYFSFEKIPFAKPPLGELRFRAPVP 56
            :||..|.:       :.||     |::.| |.:||  :..|...|..:||||||||.|||..|.|
  Rat     9 ASLAACPIWASGHPSSPPVVDTTKGKVLG-KYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEP 72

  Fly    57 ADPWSGVLDCTHYAEKPTQRGLLTR-------------EIEGGEDCLYLNVYS-KQLKSEKPLPV 107
            |:|||.|.:.|.|....:|.|::.:             .:|..|||||||:|| ..|.....|||
  Rat    73 AEPWSFVKNTTTYPPMCSQDGVVGKLLADMLSTGKENIPLEFSEDCLYLNIYSPADLTKNSRLPV 137

  Fly   108 MVYIYGGAFTVGEATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLA 172
            ||:|:||...:|.|: ...|......::||:||:.||:...|..|..|...:  ||....||:.|
  Rat   138 MVWIHGGGLIIGGAS-PYSGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSR--GNWAHLDQLAA 199

  Fly   173 LKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTV--HNYWANNPAE 235
            |:||:..|:||.|:..::|:|||||||.|...::.:...:.|||:||..||.|  .|....| .:
  Rat   200 LRWVQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSPLAKNLFHRAISESGVVLTTNLDKKN-TQ 263

  Fly   236 DFAFRLAQQNGFTGENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCV 300
            ..|..:|..:| ......|.:::.|:.....:|:.            |......|..:.|.:..|
  Rat   264 AVAQMIATLSG-CNNTSSAAMVQCLRQKTEAELLE------------LTVKLDNTSMSTVIDGVV 315

  Fly   301 VPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKE 365
            :||.|.|:..:...|..|.::|....|..::.|.:..||.:...:::   ::....:|..|   .
  Rat   316 LPKTPEEILTEKSFNTVPYIVGFNKQEFGWIIPTMMGNLLSEGRMNE---KMASSLLRRFS---P 374

  Fly   366 NLEYSQRLMKAYF-----GYSPPS--SELLLNMLDFYSYKIFWHGFNRTFNAR-LTYAKAPTYYY 422
            ||..|:.::.|..     |...|:  .||||:|..    .:|: |......:| |..|.||||.|
  Rat   375 NLNISESVIPAIIEKYLRGTDDPAKKKELLLDMFS----DVFF-GIPAVLMSRSLRDAGAPTYMY 434

  Fly   423 RFDFDSPNFNFYRAKFCGDKIKTGVA--HADDLSYLFRNAGSWKLDKTSAEYRT-IERMI-GIWT 483
            .|.        ||..|..|:....|.  |.|::..:|   |:..|.:.::|..| :.::: ..|.
  Rat   435 EFQ--------YRPSFVSDQRPQTVQGDHGDEIFSVF---GTPFLKEGASEEETNLSKLVMKFWA 488

  Fly   484 AFAATSNPNCPEIGHLEWKPSTKNDPKR-VINISSDVTIIDLPEYEKLQIWDNLYKPN 540
            .||...|||...:.|  |   .:.|.|. .:.|.:........:.|::..|..|...|
  Rat   489 NFARNGNPNGEGLPH--W---PEYDQKEGYLQIGATTQQAQKLKGEEVAFWTELLAKN 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	162/563 (29%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	162/554 (29%)