Protein Alignment alpha-Est5 and Ces2b

DIOPT Version :10

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 543
• Identity: 156/543 - (28%)
• Similarity: 250/543 - (46%)
• Gaps: 75/543 - (13%)

  Fly    18 GQIKG----VK--RLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQR 76
            ||::|    ||  :..::     :|..|||||||:|.|||..|...:|||||.|.|.:.....|.
Mouse    41 GQVRGSLVHVKDTKAGVH-----TFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQN 100

  Fly    77 GLLTREIE-------GGEDCLYLNVYSKQLKSE-KPLPVMVYIYGGAFTVGEATRELY-GPDYFM 132
            ..:.:||:       ..|||||||:|:.....| ..|||||:|:||....|.|:  :| |.....
Mouse   101 LGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGGLVAGMAS--MYDGSLLAA 163

  Fly   133 TKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESA 197
            .:|:|:||:.||:..|||.|..|...:  ||.|..|||.||:|::|.|::|.|....:|:|||||
Mouse   164 IEDLVVVTIQYRLGVLGFFSTGDQHAR--GNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESA 226

  Fly   198 GGCSTHFMMCTEQTRGLFHKAIPMSG-TVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQ 261
            ||.|....:.:..::||||.||..|| .:..|...:.:|..:..:|:.:|....:.:| ::..|:
Mouse   227 GGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGCEAMDSEA-LVRCLR 290

  Fly   262 GVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYV-GEDCVVPKPPVEMARDAWSNNFPVMLGGTS 325
            |....:::..|.|.             ..:.|.| ||  ..|:.|.|:......:..|.::|..:
Mouse   291 GKSEAEILAINKLV-------------QMIPAVVDGE--FFPRHPKELLASEDFHPVPSIIGVNN 340

  Fly   326 FEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLN 390
            .|..:..|.|..:.:.:..::::  .|..|...|.:......|.|..||:.|.|.:..:..|.:.
Mouse   341 DEFGWTIPVVMGSAQTIKEITRE--NLQAVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQ 403

  Fly   391 ----MLDFY----SYKIFWHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGV 447
                |.||.    :.::.:  |.|        :.|..|:|.|.....:....|.    ..:|..
Mouse   404 FTEMMEDFMFVIPALQVAY--FQR--------SHASVYFYEFQHQIASLKDVRP----THVKAD- 453

  Fly   448 AHADDLSYLFRNAGSW--KLDKTSAEYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDPK 510
             |||::.::| ....|  |||.|..|.....||:..|..||...|||...:.:  | |...:| :
Mouse   454 -HADEIPFVF-GYFFWDMKLDFTEGEKLLSRRMMKYWANFARHGNPNSEGLPY--W-PVMDHD-E 512

  Fly   511 RVINISSDVTIIDLPEYEKLQIW 533
            :.:.:.:...:....:..:||.|
Mouse   513 QYLQLDTQPAVGRALKSRRLQFW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	155/541 (29%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	155/541 (29%)