Protein Alignment alpha-Est5 and cest-31

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 168/556 - (30%)
• Similarity: 253/556 - (45%)
• Gaps: 117/556 - (21%)

  Fly    10 TCELTLPVGQIKGVKRLSLY---DDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAE 71
            ||      |.::|    :||   ::....:..||:|:||:|.|||:.||.||.|:...|||.|..
 Worm    20 TC------GPVQG----NLYRHGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGP 74

  Fly    72 KPTQRGLL-------TREIEGGEDCLYLNVYSKQ--LKSEKPLPVMVYIYGGAFTVGEATRELYG 127
            :....|:|       ..:|....:||.|||:..|  :|.....|||::|:||.|.: .|:::..
 Worm    75 RCPPSGMLYENLQLPNTDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFIHGGGFEL-SASKDYC- 137

  Fly   128 PDYFMT-----KDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDD 187
             ||.::     |||::||:||||..||||:..|.|.:  ||.||.|..||||||..:||:|.||.
 Worm   138 -DYSLSGTLPLKDVIVVTVNYRVGALGFLTTGDDSCR--GNFGLWDLTLALKWVSTHISSFGGDP 199

  Fly   188 SNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFA---FRLAQQNGFTG 249
            .|:|:||:|||......:..:..:|.||||.|.|||:.|..:|....|:.|   ...|:..||:|
 Worm   200 KNVTLFGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEYARSRGFSG 264

  Fly   250 ENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLL------FAFGPTVEAYVGEDCVVPKPPVEM 308
             :..|::||:.:.:|...|:         .:.||.      .:|.|.::   |:  ..|||..|:
 Worm   265 -SGSAELLEFFENLPIEKLL---------EKTGLKHTVSIDLSFAPNLD---GD--FFPKPLEEL 314

  Fly   309 ARDAWSNNFPVMLGGTSFEGLFM------YPAVSANLKALDSLSQDPTRLVPVDVRTVSSE---- 363
            .|:  :...||::|....|||..      :.....|.|                 |.|.||
 Worm   315 RRE--TRKKPVIVGMMEDEGLITAFADGDFTTCEENFK-----------------RRVESEYRGD 360

  Fly   364 -KENLEYSQR-LMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPTYYYRFDF 426
             .||.|..|: :|..|..|...|.|  ..::|:..:.::..|...:..: |..|....|:|.|||
 Worm   361 VVENPENVQKNIMNFYTNYCDESEE--RKLVDYIGHSVYNAGVLLSAES-LARAGNCVYFYVFDF 422

  Fly   427 DSPN----------FNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMIGI 481
            .:|:          |.             |.||..:|.|:.......|.|....:.:.:|.|..:
 Worm   423 WNPDGFGPVGSIVPFK-------------GAAHCSELRYIIGEGVYSKFDANEKDLKMMEYMTTM 474

  Fly   482 WTAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISS 517
            :|.||...|||.|  |...|:  |..:..|..:|.|
 Worm   475 FTNFAKYGNPNIP--GVTNWE--TYTEGSRHFHIDS 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	165/547 (30%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	168/556 (30%)
		Aes	<112..>211	CDD:223730	48/103 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.720