Protein Alignment alpha-Est5 and cest-7

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 131/555 - (23%)
• Similarity: 238/555 - (42%)
• Gaps: 87/555 - (15%)

  Fly    18 GQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHY-AEKPTQRGLLTR 81
            |:::|:...|...:..:.|:.|||||||||.|||..|...:.|:||||.:.| |...:...|.:.
 Worm    45 GKVRGITDFSDKRNHKYIFKGIPFAKPPLGLLRFALPEEPNTWNGVLDGSKYSAACLSNSSLASA 109

  Fly    82 EIEG-GEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDYFMTK-----DVVLVT 140
            :.|. .|||||:|:::.:.......||:||.:||:|.:..||   ..||.|:.:     .:|...
 Worm   110 QQENISEDCLYINIFTSEYCLAHKCPVLVYYHGGSFNLDSAT---MFPDKFILERYVDSGIVFAI 171

  Fly   141 LNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFM 205
            ..||:...|...|.:..: ||.|..:.|.:.:|.:|...|::|.||.:.:|:.|.|:||...:.|
 Worm   172 PAYRLGVFGQFYLGEQGI-VPANLLIHDCIRSLNFVHDNIASFGGDPNYVTLMGHSSGGQLVNAM 235

  Fly   206 MCTEQ---TRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARD 267
            ..:.|   .:.||.:.|.:| ::..|...:.....::.:|:::..|.||.. ::::.::.:.|..
 Worm   236 GFSNQIDPEKKLFQQFIVLS-SIGMYGFEDLQIGNSYEIARRHNCTSENSQ-EIVDCMRNIDALQ 298

  Fly   268 LVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPV--------EMARDAWSNNFPVMLGGT 324
            |:....:..:   ..|||.           ..::..||:        |...:..:.|  ::.|.|
 Worm   299 LLQTQTVMDD---VDLLFF-----------KAIIRAPPLMDVKQKLSEFKENVTARN--MLCGVT 347

  Fly   325 SFE-GLFMYP---AVSANLKALDSLSQDP-----------TRLVPVDVRTVSSE--KENLEYSQR 372
            ..| .:|.||   .:||..  ||  .::|           |.:.|..|.:.||.  .....||:.
 Worm   348 DNEFTIFKYPDGYYISATF--LD--FENPVDTVNVYRNKFTNITPTFVNSDSSAVFVSAATYSEA 408

  Fly   373 LMKA---YFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLT-------YAKAPTYYYRFDFD 427
            |..|   .:.:........:::.|..    ::.|.:|..|....       |:|....:.:|...
 Worm   409 LTNAGGNVYLFESRQKPFSMHVTDMQ----YFIGIHREKNHTTDMDILDSFYSKLLVNFTKFGSP 469

  Fly   428 SPNFNFY---RAKFCGDKIKT--GVAHADDLSYLFRNAGSWKLDKTSAEYRTIE-RMIGIWTAFA 486
            |||:..|   :..|...:|.|  |:....:..:.......|.::....:...|| ::.|.:.:|.
 Worm   470 SPNWEKYDPSKMNFMAMEIDTEQGIEPKMENGFHEELVNFWLINMMQIDRNIIEMKLNGEYNSFD 534

  Fly   487 ATSNPNCPEIG-----HLEWKPSTKNDPKRVINIS 516
            ..:......||     .:.:.|:. :||:.:..||
 Worm   535 GRAQLTTKHIGVPTSLPIIYAPAV-SDPENLELIS 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	128/547 (23%)
cest-7	NP_001257187.1	Abhydrolase	34..510	CDD:304388	119/494 (24%)
		Aes	<135..>236	CDD:223730	32/104 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840