Protein Alignment alpha-Est5 and cest-16

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 155/612 - (25%)
• Similarity: 252/612 - (41%)
• Gaps: 124/612 - (20%)

  Fly    21 KGVKRLSLY--DDPYFS-FEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQ------- 75
            :|:.|.::|  |..:.. |..:|:|:||:|||||:.||....|...|....|.....|
 Worm    30 QGLVRGNIYNIDGKHIQIFRGVPYAEPPIGELRFKPPVKKTRWHQELPAVEYGPPCLQFMDFHKN 94

  Fly    76 -RGLLTREIEGGEDCLYLNVYSKQLKSE--KPLPVMVYIYGGAFTVGEATRELYGPDY------F 131
             :...|......||||||||:|.....:  |..|::|:|:||:|..|.|..   |.|.      .
 Worm    95 DKFAKTNMDRQSEDCLYLNVFSPYDTDDESKTYPILVWIHGGSFLAGSADT---GIDMEVIAANI 156

  Fly   132 MTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGES 196
            ::|.:..|::|||:..|||::.::.. |:.||.|:.|.|:||:|::..|..||||.:.:||.|||
 Worm   157 VSKGIAFVSINYRLGPLGFMNYQNGD-KLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMGES 220

  Fly   197 AGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWA----NNPAEDF-----AFRLAQQNGFTGEND 252
            |||.::..:..:.:|.||.|:||.|||:....||    :.||...     .||..:   :..|:|
 Worm   221 AGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEK---WINEDD 282

  Fly   253 DAKVL--EY---LQGVPARDLVNH-----NLLTPEHR--------RNGLLFA---FGPTVEAYVG 296
            ..:|:  ||   ...|....|.|:     |.||.:..        |..|.|:   |...:.|.:|
 Worm   283 TKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKMNCLRKELNFSSPLFRKALAAELG 347

  Fly   297 ------EDCVVPKPPVEMARDAWSNN--FPVMLGGTSFE-----GLFMYPAVSANLKALDSLSQD 348
                  :..:||...|.:.|    ||  .|:|.|....|     .:|........||..| :.:.
 Worm   348 VSKMVVDGDLVPSSGVSLVR----NNARIPIMTGVARKEWGHKKAMFYNMHQRDGLKRSD-VEEQ 407

  Fly   349 PTRLVPVDVRTVSSEKENLEYSQRLMKA----YFGYSPPSSELLLNMLDFYSYKI-----FWHGF 404
            ..|::.......:|||......|.:..|    |.  ..|::|.:.:.:.....|:     |....
 Worm   408 VYRIIDNSFHETASEKLANSTVQLIANATIVRYL--ETPNNEFIADQVVGALQKLESDIEFVAPC 470

  Fly   405 NRTFNARLTYAKAPTYYYRFDF--DSPNFNFYRAKFC--GDK------------IKTGVAHADDL 453
            .|...|.:... .|.|.|.||:  .||.....|..:.  |.|            ::....|..|.
 Worm   471 EREVAAYVDKG-VPVYLYSFDYVPKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDH 534

  Fly   454 SYLFRN--AGSWKLDKTSAEYRTIERMI-GIWTAFAATSNPNCPEIGHLEWKPSTKNDPKRVINI 515
            :::|..  :.::::...:....|:.::: .:.|.|....:|:..   ...|...:.|
 Worm   535 AFIFSKGYSSNFEISPYTKREETMSKILCTMLTNFVKNGDPSTT---RFSWPIFSGN-------- 588

  Fly   516 SSDVTIIDLP--------EYEKLQIWD 534
            ||....:|:|        .:...|.|:
 Worm   589 SSQYVSLDVPLKLLEGEIHFPDAQFWN 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	149/578 (26%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	153/603 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810