Protein Alignment alpha-Est5 and cest-26

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 163/583 - (27%)
• Similarity: 257/583 - (44%)
• Gaps: 119/583 - (20%)

  Fly    18 GQIKGVKRLSLYDDPYFS-FEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGL--- 78
            |.::|. |:.:.||.... |..|||||.|:|:|||:.|...:.|.||..|..:..:..|...
 Worm    49 GLVEGF-RIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQADFFWE 112

  Fly    79 -LTREIEGGEDCLYLNVYSKQLKSEKPL----PVMVYIYGGAFTVGEATRELYGPD----YFMTK 134
             .|..:...||||||||:|...|:|:..    |||||::||.|.:..|.:  ||.:    |....
 Worm   113 RFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVK--YGDEGIAKYLCRH 175

  Fly   135 DVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGG 199
            .||:||:.||:..|||.|..|.  ..|||.||.|..:||:||:..:..|.||...:||||:||||
 Worm   176 GVVVVTIQYRLGLLGFFSTGDQ--VCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGG 238

  Fly   200 CSTHFMMCTEQTRGLFHKAIPMSGTVHNYWAN-------NPAEDFAFRLA-QQNGFTGENDDAKV 256
            .|...:..:..:|.|||:.:||:|.....|:.       |...:||:|.. .:.....||....:
 Worm   239 VSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNACREFAYRKCWDEKQARDENASESM 303

  Fly   257 LEYLQGVPARDLVNHNLLTPEHRRNGL-LFAFGPTVEAYVGE--DCVVPKPPVEMARDAWSNNFP 318
            ||:|:....|:. ...|||    |.|: :...|..:...:|.  ...:||...|:.::|...|
 Worm   304 LEFLRTRKEREF-EKRLLT----RKGVDVSKIGLDLAPVIGSKPSDFLPKSIEELRKEAPKKN-- 361

  Fly   319 VMLGGTSFEGLFMYPAVSANL--KALD----------------SLSQDPTRLVPVDVRTVSSEKE 365
            :|:|....|||.......:|.  |.:|                :|.::..::.   ::.:|.:::
 Worm   362 IMVGTCEHEGLLFASLGPSNFDEKGIDKLLALLITEENHEDFEALREEAKKMY---LKKLSDDED 423

  Fly   366 NLEYSQRLMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPT------YYYRF 424
            :.|.:.|      ||....|:|.:|              |.|:|    ||:..|      :.|.|
 Worm   424 DKEVAAR------GYIQLYSDLFVN--------------NGTYN----YAEKMTKLGNKVFMYSF 464

  Fly   425 DFDSP-NFNF--YRAKFCGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMIGIWTAFA 486
            |:.:| :|..  .||.|      ....|..:|:|:|..:..:......::...::.|..:||.||
 Worm   465 DYCNPRSFGILSLRAPF------RAATHCTELAYIFGVSIVFNYRYNESDRAMLDLMTKMWTNFA 523

  Fly   487 ATSNPNCPEIGHLE--------WKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDNLYKPNQ 541
            ...|||    |..|        |:|::|.:|...:.|:           ||......:|:.|:
 Worm   524 KYGNPN----GQYEDSTVFDFKWEPTSKEEPTNFLAIN-----------EKKCEMQTVYQDNR 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	157/550 (29%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	163/583 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.720