Protein Alignment alpha-Est5 and cest-1.1

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 143/578 - (24%)
• Similarity: 240/578 - (41%)
• Gaps: 116/578 - (20%)

  Fly    15 LPVGQIKGVKRLSLYDDPYFS-----FEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPT 74
            |..|.|:| |.|::...|..:     |..|||.:||:|:||:|.|.|...|.|||....|.....
 Worm    21 LSSGTIEG-KILNISYSPLGNQSATVFLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTNEYKSACM 84

  Fly    75 QRGLLTREIEGG----EDCLYLNVYSKQLKSE-KPLPVMVYIYGGAFTVGEATRELYGPDYFMT- 133
            .....|.:.:.|    ||||||||.:.:...| |...||:.::||.:....|:  .:.|:..:.
 Worm    85 SNATKTYKNKFGGPISEDCLYLNVLTNEYCLENKNCSVMMIVHGGGYLTESAS--TFNPEILINN 147

  Fly   134 -----KDVVLVTLNYRVDCLGFLSLK-DPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITV 192
                 :::|:||.|||:....|.... |...|   |.||.|.:.::.||::.|.||.|:.:.||:
 Worm   148 FVGQGRNIVVVTFNYRLGLFSFGQFNGDRGDK---NFGLYDMIESVNWVRREIENFGGNKNRITL 209

  Fly   193 FGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVL 257
            .|.|||.........:..|:||.|:.|.||..:.|             :::::.|.|....|:::
 Worm   210 AGHSAGASMIVAFTSSPLTKGLVHQQIIMSAPMTN-------------MSKKSNFKGMTVMAQMV 261

  Fly   258 EYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDA--W-SNNFPV 319
            ..|.     :.:..|.|:.|...|           .|   .| :.|...:...||  | ..|...
 Worm   262 GCLS-----EEIGFNKLSEEQVEN-----------TY---SC-LRKKSAQQILDAQLWLLQNSTY 306

  Fly   320 MLGGTSFEGLFM--YPA---VSANLKALDSLSQDPTRLVP-----VDVRTVSSEKENLE------ 368
            .||....:..|:  ||.   .|.::..:::|....|..|.     :|......:.|.||
 Worm   307 FLGAPPIDEHFLTDYPENLYASKSIYPINTLIGTTTLEVEESSYIIDPAFADKKVELLENLCDHI 371

  Fly   369 ----------YSQRLMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPTYYYR 423
                      :|::..|.|...:  ||..|.|.::||:..|.:...:.:.|.::       :.|.
 Worm   372 GYVLYEEPETFSKKCQKQYMNGN--SSMNLSNEMEFYTPAIDFADSHTSGNTKV-------FLYS 427

  Fly   424 FDF--DSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMI-GIWTAF 485
            :|:  ..|.::.|.      :::: ..|::||.|:|   |:.:......:| .||::. |::..|
 Worm   428 YDYRGAGPAYDRYL------EVRS-PHHSEDLIYVF---GTHRGIFAPKDY-IIEKIYSGMFADF 481

  Fly   486 AATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTII-----DLPEYEKLQIWDNLYK 538
            ....|| .|. |..:|...||.:.:..: |:.|...|     |....|..:.|..:.|
 Worm   482 VNFENP-LPS-GDQKWNQYTKENREHFL-INFDKNFITPGMRDNYYTEAYEFWSTVGK 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	136/543 (25%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	141/571 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157093
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740