Protein Alignment alpha-Est5 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 133/521 - (25%)
• Similarity: 210/521 - (40%)
• Gaps: 137/521 - (26%)

  Fly     3 SKESSLETCELTLPVGQIKGVKRLSLYDDPY-----FSFEKIPFAKPPLGELRFRAPVPADPWSG 62
            |.:.::.| ::.|..|.|:| |:|:....|:     .:|..||:.:||:|:||||.|.|...|||
 Worm    12 SAQFAIST-KVQLSTGIIEG-KQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSG 74

  Fly    63 VLDCTHYAEKPTQRGLLTREIEGG-------EDCLYLNVYSKQLKSE-KPLPVMVYIYGGAFTVG 119
            ||:...:  ||......|:..:.|       ||||||||.:.|...| |...|::.::||.:...
 Worm    75 VLETKKF--KPACMSNSTKTYKNGGIGGPISEDCLYLNVLTNQYCLENKNCSVVIIVHGGGYLFE 137

  Fly   120 EA--------TRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWV 176
            .|        .....|.|    :::|:||:|||:...||..|.  ..:...|.|:.|.:.|:|||
 Worm   138 SAATFNHEILVNNFVGQD----RNIVVVTINYRLGIFGFGHLN--GFEGDKNVGIFDTLEAVKWV 196

  Fly   177 KQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRL 241
            ::.|..|.|:...||:.|.|||.........:..|:||.|:.|.|||.:.|             :
 Worm   197 RREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSGPMTN-------------M 248

  Fly   242 AQQNGFTG---------------------ENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLF 285
            ::::.|.|                     |::..:|...|:..||::|::..|...::.    .|
 Worm   249 SKKSNFKGMTAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKKPAQELLDAQLWLLQNS----TF 309

  Fly   286 AFGPTVEAYVGEDCVVPKPPV--EMARDAWSN--------NFPVMLGGTSFE----------GLF 330
            .||              .|||  |...|...|        :...:||.|:.|          ...
 Worm   310 YFG--------------APPVDGEFITDYPDNLYSEKSIFSINTLLGTTTRELQDTGYISNSNYS 360

  Fly   331 MYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNMLDFY 395
            .:......||.|            .|...:...||:.::|.:..|.|...|  .|:.|.:.::||
 Worm   361 KFETKETFLKNL------------CDQIGIEIYKESEDFSSKCQKWYINGS--DSKSLSDDMEFY 411

  Fly   396 SYKIFWHGFNRTFNARLTYA----KAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYL 456
            :..|         |....:|    |...|.|.:....|.|..|.      |:|: ..|::||.|.
 Worm   412 TQAI---------NLADAHARKGKKVYMYSYAYSGAGPAFKKYM------KVKS-PHHSEDLIYT 460

  Fly   457 F 457
            |
 Worm   461 F 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	132/517 (26%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	131/511 (26%)
		Aes	<125..>250	CDD:223730	40/143 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740