Protein Alignment alpha-Est5 and cest-17

DIOPT Version :10

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 153/573 - (26%)
• Similarity: 235/573 - (41%)
• Gaps: 100/573 - (17%)

  Fly    12 ELTLPVGQIKGVKRLS-LYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGV-LDCTHYAEK-- 72
            ::|.|.|.|.|.:..| :....|..|..|.:..||....||:.|.|.:.|..: .|.||:...
 Worm    23 KVTTPYGPIVGFEHKSTVTGSKYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCI 87

  Fly    73 PTQRGLLTREIEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELY--GPDYFMTKD 135
            |:.|..|..::...||||:||:.:.....||.|||:|:|:||.|..|:.:...|  ..|.|::||
 Worm    88 PSLRSELEEQVNYSEDCLFLNIVTPPDAKEKKLPVLVFIHGGGFQFGDTSMIGYQKAADNFVSKD 152

  Fly   136 VVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGC 200
            ::.|::.||:..|||.:..|.  ::|||.||.||.|||:::.:.:.:|.||...||:.|.|||..
 Worm   153 IIFVSIQYRLGPLGFFTTGDS--EIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGAA 215

  Fly   201 STHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVP- 264
            |...::.:..:..||.:||.:||::               .::.|......||::.|....|.|
 Worm   216 SVSALLYSPHSDHLFSQAIQLSGSI---------------FSESNLDRNVVDDSRKLAKAAGCPQ 265

  Fly   265 -----ARDLVN----HNLLTPEHRRNGLLFAFGPTVE---AYVGEDCVVPKPPVEMARDAWSNNF 317
                 .||.:.    ..||........||  .||..:   .|..:| ..|....:|:|.|....
 Worm   266 EDSKELRDCIEIRTVDELLDAMESIGELL--PGPRTKKFHPYFDKD-FFPYDIEKMSRKAPKKR- 326

  Fly   318 PVMLGGTSFE-GL-FMYPAVSANL-----KALDSLSQDPTRLVPVDVRTVSSEKENLEYSQR--- 372
             .|.|..|.| || .:||...|.|     ::..:.|:|  .||......|:.|:|....|.|
 Worm   327 -TMQGLVSLESGLSVLYPVKLAKLLGVPKESWSTYSKD--NLVDFIRSQVAVEQEFGTASARFSG 388

  Fly   373 LMKAYFGYSPPSS------ELLLNMLDFYSYKI---------FWHGFNRTFNARLTYAKAPTYYY 422
            |::.::...|.:.      ....|:|....|.|         ..||::             ||.|
 Worm   389 LVEEFYLSGPMTGNSSFYLNAFANLLSDLQYNIPTLHEVELKLQHGWD-------------TYLY 440

  Fly   423 RFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKL-----DKTSAEYRTIERMIGIW 482
            ..|:||..     .|.....|| |..||.:|.|||...|...:     ||....|        ..
 Worm   441 IIDYDSET-----TKDPTHPIK-GPFHASELRYLFNFNGMDTIPFNDKDKKFENY--------FV 491

  Fly   483 TAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDN 535
            .|.....|...|....|.|...:|:.|...:.::...::......|..::|.:
 Worm   492 NAIVNFINTGTPSTKALLWPAVSKSQPFANLLLNDKPSVQTSFRQEAYELWQS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	152/569 (27%)
cest-17	NP_505114.1	COesterase	22..542	CDD:395084	152/569 (27%)