Protein Alignment alpha-Est5 and cest-24

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 155/585 - (26%)
• Similarity: 245/585 - (41%)
• Gaps: 126/585 - (21%)

  Fly     3 SKESSLETCELTLPVGQ------------IKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPV 55
            |.:|::.||...|..|:            ::|.:..:...|....|..||:|:||:|||||:.|.
 Worm    76 SNQSNMGTCFSNLKSGKSENAIVRVQQGLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQ 140

  Fly    56 PADPWSGVLDCTHY------AEKPTQRGLLTREIEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGG 114
            |...|.|:..|..|      .|.|..:.|  ......||||||||::.:::.:|..||:.||:||
 Worm   141 PPKAWEGIRKCNKYPNRSIHKEMPWDKAL--PSANQSEDCLYLNVFAPKIREDKKYPVLFYIHGG 203

  Fly   115 AFTVGEATRELYGPDY--------FMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVL 171
            .:.:..|.|      |        .:::::::||.:||:..|||||..|.  ..|||.||.|.:.
 Worm   204 GYVMDSAER------YTAKNICKLLVSREIIVVTFHYRLGFLGFLSTGDD--VCPGNYGLFDMLE 260

  Fly   172 ALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAED 236
            |::||...||:|.||..|||:.|:|||..:...:..:..|:|||.:.|.|.|..:.:||.....|
 Worm   261 AMRWVHANISSFGGDPENITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHD 325

  Fly   237 -------FAFRLA---QQNGFTGENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTV 291
                   :|.||.   |.|......:...:..:..|:|...|             |:...|..|
 Worm   326 IREYCKKWAKRLGWKPQLNYANKREESVDIFNFFNGLPTSKL-------------GMTMFFSNT- 376

  Fly   292 EAYVGEDCVVPKPPV----------EMARDAWSNNFPVMLGGTSFEGLFMYPAVS---ANLKALD 343
               :.::|.:|..||          ::.|:. ..:.|.::||..:|.| ::.|:.   ...|.::
 Worm   377 ---IFKECQLPLAPVIDGEILPHDLKVLRET-QEHVPSLVGGGEYEAL-LFCAIGLLRGTEKEIN 436

  Fly   344 SLSQDPTRLVPVDVRTVSSEKENLEYS--QRLMKAYFGYSP----PSSELLLNMLDFYSYKIFWH 402
            |         .:|   |.|.|..|..|  :.:.:..:|.||    .|....:..:...| .||.:
 Worm   437 S---------AID---VLSRKNRLSRSKIEAMTEKVYGDSPALRADSKARKMFFVQLIS-DIFAN 488

  Fly   403 GFNRTFNARLTYAKAPTYYYRFDFDSP---NFNFYRAKFCGDKIKTGVAHADDLSYLF------R 458
            ..|..|...........|.|.||..|.   .:..:...|      ||..|..:|||||      .
 Worm   489 YGNYRFMRDCQQRGVECYGYSFDHQSKQMWGWLQHVVPF------TGGTHTSELSYLFDCNYMSA 547

  Fly   459 NAGSWKLDKT----SAEYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDP-KRVINISSD 518
            ..|..|.||.    :|:|         :|.|.....||.|.....:|:..:.:|. .::|:|..:
 Worm   548 PLGMNKTDKVVSGMTADY---------FTNFVKFGTPNGPNSQLPKWERISPDDEHMKLISIKPE 603

  Fly   519  518
             Worm   604  603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	151/571 (26%)
cest-24	NP_504613.1	COesterase	97..608	CDD:278561	149/564 (26%)
		Aes	<183..>285	CDD:223730	39/109 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I1478
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2231
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870