Protein Alignment alpha-Est5 and cest-35.1

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 172/606 - (28%)
• Similarity: 248/606 - (40%)
• Gaps: 178/606 - (29%)

  Fly    13 LTLPVGQIKGVKRLSLYD------DPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAE 71
            |....|.|:|    ::|:      |.|..   |||||.|:|||||:..|.|:.|:..|||..|..
 Worm    17 LNASCGPIRG----NIYEHDDKIVDGYLG---IPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGP 74

  Fly    72 KPTQRGLLTREI--------EGGED-CLYLNVYSKQLKS-EKP--LPVMVYIYGGAFTVGEATRE 124
            ...|.|.|...|        |..|| ||.|||::.:.|| |.|  |||:||.|||.|.||.::
 Worm    75 GCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEVGFSS-- 137

  Fly   125 LYGPDYFMT-----KDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFN 184
             ...||.:|     |||:|||.|||:..|||.:..|...:  ||.||.||.|||:||:::|.:|.
 Worm   138 -MFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVSR--GNWGLWDQALALQWVQKHIKSFG 199

  Fly   185 GDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNP-------AEDFAFR-L 241
            ||.||:|:.|.||||.|..|:..:......|||.|||||.     |..|       .|...|| .
 Worm   200 GDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGA-----ATCPFGIRSKDVEGLIFREF 259

  Fly   242 AQQNGFTGENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGL------LFAFGPTVEAYVGEDCV 300
            |:.:|:.| ||...:|.:.|...|...:         :..|.      :|:|.|.   |.|:  .
 Worm   260 AKHHGYAG-NDSESLLHWYQSQDAEIFL---------KAEGFKYPASGMFSFVPN---YDGD--F 309

  Fly   301 VPKPPVEMARDAWSNNFPVMLGGTSFEGL---FMYP---------------------------AV 335
            .|||..|:.::|  .....::....:|||   ..||                           ||
 Worm   310 FPKPFDELRKEA--PKLDAIVSVAEYEGLGFEEFYPGQKSPQEVLTAALGPEVVRNREEVVKKAV 372

  Fly   336 SANLKALDSLSQDP--TRLVPV------DVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNML 392
            .|.|:.::..|.:.  .:||.:      .|....:.:...:|...:..:.|.|..|.:.::.
 Worm   373 EAYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGNNVYLSSFNYFNPETPIMF--- 434

  Fly   393 DFYSYKIFWHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLF 457
                      |.||.|||                                    .:|..|:.|:.
 Worm   435 ----------GENRPFNA------------------------------------ASHGCDIRYIL 453

  Fly   458 RNAGSWKLDKTSAEYRTIERMIGIW-TAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTI 521
            .:.    :.:.|.|.|.:..|:|.: |.||...|||...:. :.|:..:.::|.|...|
 Worm   454 GDG----IGEFSKEDRKVMDMMGTYLTNFAKYGNPNGKGVS-IPWEKYSLDNPGRYFKI------ 507

  Fly   522 IDLPEYEKLQIWDNL----YK 538
                :|.|.::.||.    ||
 Worm   508 ----DYPKCEMADNFLDGRYK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	163/572 (28%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	168/596 (28%)
		Aes	<106..>214	CDD:223730	53/112 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157239
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650