Protein Alignment alpha-Est5 and cest-6

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 138/534 - (25%)
• Similarity: 224/534 - (41%)
• Gaps: 102/534 - (19%)

  Fly     6 SSLETCE---LTLPVGQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCT 67
            |:.::||   :|..:|.|.|.:..|     |.:|:||||||||:|:|||:.|:.|:.|.|:|:.|
 Worm    16 SAYKSCEAGVITTSLGSINGNQIGS-----YQTFKKIPFAKPPIGKLRFQKPMAAEKWEGILNAT 75

  Fly    68 HY---------AEKPTQRGLLTREIEGGEDCLYLNVYSKQ-LKSEKPLPVMVYIYGGAFTVGEAT 122
            .|         ..|..|:.:       .||||::|:::.. ..|.|...|:.|::||......|.
 Worm    76 EYGPACMSNSSTSKSPQKWI-------DEDCLHINIFTTDTCLSSKNCSVVFYVHGGELVYDSAV 133

  Fly   123 --RELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNG 185
              .:.|..|.|.::||:||...:|:.......::|.:: .|.|..|.|.:|||::||..|.||.|
 Worm   134 MFEDKYLFDTFSSRDVILVIPAFRLGLFSHFVVEDQNV-APNNLALYDILLALEFVKSEIHNFGG 197

  Fly   186 DDSNITVFGESAGGCSTHFM-MCTEQTRGL--FHKAIPMSGTVHNYWANNPAE-DFAFRLAQ--- 243
            ....:|.||.|.||.....| ..||....|  |.:.|.||..  |.|.:...| :...|..|
 Worm   198 SSDRVTAFGHSYGGHVVSVMAFSTEINTDLSYFQRVICMSSV--NVWDSLEFEIEKTMRFIQYAN 260

  Fly   244 -------QNGFTGENDDAKVLEYLQGVPARDL--VNHNLLTPEHRRNGLLFAFGPTVEAYVGEDC 299
                   ::..|....|:.::|.||.:.:.:|  :..:|....|.....|....|.::..:.:|
 Worm   261 CSVPQDLKSRMTSFEQDSYMMECLQDIDSMELLRIQRSLEDEGHPIYSGLVLREPLIQNVLVQD- 324

  Fly   300 VVPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPAVS--------ANLKALDSLSQDPTRLVPVD 356
            ...||          .|.|.:.|.| ::.|..:.|..        .|.|..|...:|..:....|
 Worm   325 FYEKP----------KNIPTLTGCT-YKELDKFHAYHNIVETLGYENYKECDDKYRDDRKYGRFD 378

  Fly   357 VRTVSSE------KENLEYSQRLMKA----YFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNAR 411
            :...:.|      :..|:..::|.|.    ::.||.|...   :..|..||.:..|.|.:..| .
 Worm   379 LNKHADETFGILAQTKLKVDKQLDKGIPTYFYEYSYPKHP---SHTDDLSYIMGVHAFEKDEN-E 439

  Fly   412 LTYAKAPTYYYRF----DFDSPN-------------FNFYRAKFCGDK--IKTGVAHADDLSYLF 457
            :..||  :|...|    .|..|.             ||||..:..|:|  :||.. ..:.:.|..
 Worm   440 IHLAK--SYQEMFMNFVKFGEPGGGFEMSTFENSSYFNFYWNETTGEKSSMKTNF-EKEIIKYWL 501

  Fly   458 RNAGSWKLDKTSAE 471
            ::...:..:.|:|:
 Worm   502 KDMFEYDQNITAAK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	137/533 (26%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	132/508 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156946
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740