Protein Alignment alpha-Est5 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 136/558 - (24%)
• Similarity: 218/558 - (39%)
• Gaps: 123/558 - (22%)

  Fly    17 VGQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGLLTR 81
            :|:::|.:     ...|..|.:|||||||:|.|||:.|..|:.|:||.:.|.|..........|:
 Worm    28 LGRLEGKQ-----SGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSNSTWTQ 87

  Fly    82 EIEG--GEDCLYLNVYS--KQLKSEKPLPVMVYIYGGAFTVGEAT--RELYGPDYFMTKDVVLVT 140
            ..:.  .||||::|:::  |.||| |...|:|||:||......|.  .:.:..:.|:.:||:||.
 Worm    88 SPQKWVDEDCLHVNIFTSDKCLKS-KDCAVVVYIHGGEIVFDSAVMFNDTFLLESFVKQDVILVI 151

  Fly   141 LNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFM 205
            ..:|:......::.|.:: .|.|..|.|.:||.::||..|.||.||...||:||.|.||.....|
 Worm   152 PAFRLGIFSHFTVHDQNI-APNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTIASMM 215

  Fly   206 MCT---EQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARD 267
            ..:   .|...||.:.|.||           |..:...|.:|.    |..|..|......||.
 Worm   216 AFSSEINQDLSLFQRIIVMS-----------ANQYFDTLEEQI----ERSDRVVKHAGCSVPT-- 263

  Fly   268 LVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEM---ARDAWSNNFPVMLGGTSFEGL 329
                ||....:|..         .|.|:.: |:.....:|:   .|......:| .:|.....|.
 Worm   264 ----NLARKMNRSQ---------KEKYMMK-CLQKLSGMELLSVQRSLEEAGYP-DIGNLVLRGP 313

  Fly   330 FMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNMLDF 394
             ::|.|: :|:.|:|     .:::|:.......|.:: |.....:..:||...|..      .|.
 Worm   314 -LFPDVT-SLEMLES-----PKMIPMLAGCTKFESDD-EDETHFIGKHFGLENPIE------CDE 364

  Fly   395 YSYKIFWHG-FNRTFNARLTYA---------------KAPTYYYRFDFDSPNFNFYRAKFCGDKI 443
            ...|...:| |:|..::..|.|               ..|.|.|.|.:....|
 Worm   365 KYRKDLENGIFDRQNHSDKTQAIMVPTKLRVDQLRKHGVPAYLYEFTYPKHAF------------ 417

  Fly   444 KTGVAHADDLSYLFRNAGSWKLDKTSAE------YRTI--------ERMIGIWTAFAATSNPNCP 494
                 |.|||.|:.   |....:|...|      ||.:        |..:|.     ..|:.|..
 Worm   418 -----HTDDLYYIM---GIHPFEKDENEEHLEKVYRNMLINFIKFGEPGMGF-----EMSDLNES 469

  Fly   495 EIGHLEWKPSTKNDPKRVINISSDVT---IIDLPEYEK 529
            ....:.|..:|...|:.......::|   :.::.||::
 Worm   470 TYFEIYWNETTGQKPRMRKRFEENITNYWLKEMMEYDR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	132/534 (25%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	134/547 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740