Protein Alignment alpha-Est5 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 161/636 - (25%)
• Similarity: 243/636 - (38%)
• Gaps: 174/636 - (27%)

  Fly    18 GQIKGVKRLSLYDD---PYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEK-PTQRGL 78
            |:::|. |:.|..:   |...:..:|:|.||:||.||..|.|...|||:.:.||:... |.....
  Rat    49 GKLRGA-RVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHT 112

  Fly    79 LTREI------------------EGGEDCLYLNVY-----SKQLKSE---KP------------- 104
            ...|:                  |..|||||||||     .|::..|   ||
  Rat   113 AVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAK 177

  Fly   105 ----------------------LPVMVYIYGGAFTVGE------ATRELYGPDYFMTKDVVLVTL 141
                                  .||||||:||::..|.      :....||       :|:::||
  Rat   178 KQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------NVIVITL 235

  Fly   142 NYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMM 206
            ||||..|||||..|.:.|  ||.||.||:.||:||.:.|:.|.||...|||||...|......:.
  Rat   236 NYRVGVLGFLSTGDQAAK--GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT 298

  Fly   207 CTEQTRGLFHKAIPMSGTVHNYWANN--PAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARDLV 269
            .:..:.|||.:||..||:..:.||.|  |.: :...||.:.| ....|...:::.|:...|::||
  Rat   299 LSHHSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKVG-CNVLDTVDMVDCLRQKSAKELV 361

  Fly   270 NHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPA 334
            ..::....:.     .||||.::   |:  |:|..|..:.......|:.:|||....|||.....
  Rat   362 EQDIQPARYH-----VAFGPVID---GD--VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEG 416

  Fly   335 VSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNMLDF-YSYK 398
            |......:.....|         .:||:..:||          :|| |...:.|...:.| |:
  Rat   417 VVDPEDGVSGTDFD---------YSVSNFVDNL----------YGY-PEGKDTLRETIKFMYT-- 459

  Fly   399 IFWHGFNRTFNARLT--------------------YAK--APTYYYRFDFDSPNFNFYRAKFCGD 441
             .|...:.....|.|                    :|:  :|||:|.         ||.  .|..
  Rat   460 -DWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYA---------FYH--HCQS 512

  Fly   442 KIK---TGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMIG-----IWTAFAATSNPNCP---- 494
            .:|   :..||.|::.|:|........|.....:...:.|:.     .||.||.|.:||.|
  Rat   513 LMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQD 577

  Fly   495 ---------EIGHLEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDNL 536
                     ....:.|......| :..::|.....:.|.....|:..|.:|
  Rat   578 TKFIHTKANRFEEVAWSKYNPRD-QLYLHIGLKPRVRDHYRATKVAFWKHL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	156/608 (26%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	159/631 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336096
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740