Protein Alignment alpha-Est5 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 161/593 - (27%)
• Similarity: 246/593 - (41%)
• Gaps: 163/593 - (27%)

  Fly    13 LTLPVGQIKGVKRLSLYDD---PYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPT 74
            :|...|:|:|:|: .|.::   |...|..:|:|.||.||.||:.|.|..|||.:.:.|.:|....
  Rat    55 VTTNFGKIRGIKK-ELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCP 118

  Fly    75 QR---GLLTREI-----------------EGGEDCLYLNVY---------SKQL----------- 99
            |.   |.|...:                 :..|||||||:|         ||:.
  Rat   119 QNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRK 183

  Fly   100 ------------------------KSEKPLPVMVYIYGGAFTVGEATRELY-GPDYFMTKDVVLV 139
                                    .|..|.||||||:||::.  |.|..|| |.......:|:::
  Rat   184 GGPLTKTQTDDLGDNDRAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNLYDGSVLASYGNVIVI 246

  Fly   140 TLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHF 204
            |:|||:..|||||..|.:.|  ||.||.|.:.||:|..:.|..|.||...|||||..|||...:.
  Rat   247 TVNYRLGVLGFLSTGDQAAK--GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNL 309

  Fly   205 MMC---------TEQTRGLFHKAIPMSGTVHNYWANN--PAEDFAFRLAQQNGFTGENDDAKVLE 258
            :..         :..|:|||.:||..|||..:.||.:  ||: :|..||.:.| ...:|..:::|
  Rat   310 LTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAK-YARILATKVG-CNVSDTVELVE 372

  Fly   259 YLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGG 323
            .||..|.::||:.::....:.     .||||.::   |:  |:|..|..:.......|:.:|||.
  Rat   373 CLQKKPYKELVDQDVQPARYH-----IAFGPVID---GD--VIPDDPQILMEQGEFLNYDIMLGV 427

  Fly   324 TSFEGLFMYPAVSANLKALDSL--SQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSE 386
            ...||          ||.::::  |.|.......|. .||:..:||          :|| |...:
  Rat   428 NQGEG----------LKFVENIVDSDDGVSASDFDF-AVSNFVDNL----------YGY-PEGKD 470

  Fly   387 LLLNMLDFYSYKIFWHGFN-----RTFNARLTYAK----------------APTYYYRFDFDSPN 430
            :|...:.| .|..:....|     :|..|..|..:                :|||:|.|
  Rat   471 VLRETIKF-MYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAF------ 528

  Fly   431 FNFYRAKFCGDKIK--TGVAHADDLSYL--FRNAGSWKL-----DKTSAEYRTIERMIGIWTAFA 486
              ::..:  .|::.  ...||.|::.|:  ....|..:|     .|.......:  ::..||.||
  Rat   529 --YHHCQ--TDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAV--VMTYWTNFA 587

  Fly   487 ATSNPNCP 494
            .|.:||.|
  Rat   588 KTGDPNQP 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	161/593 (27%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	161/593 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336139
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840