Protein Alignment alpha-Est5 and Ces2a

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 555
• Identity: 152/555 - (27%)
• Similarity: 236/555 - (42%)
• Gaps: 95/555 - (17%)

  Fly    18 GQIKG----VKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHY--------- 69
            ||::|    ||...   ....:|..|||||||:|.|||..|...:|||||.|.|..
Mouse    39 GQVRGSFVHVKDTK---SGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDI 100

  Fly    70 --AEKPTQRGLLTREIEGGEDCLYLNVYSKQLKSE-KPLPVMVYIYGGAFTVGEATRELYGPDYF 131
              .|...:..|:...|...|||||||:|:.....| ..|||||:|:||...||.|:..... ...
Mouse   101 MNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSASMNDVS-KLA 164

  Fly   132 MTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGES 196
            .|:::|:|.:.||:..|||.|..|...:  ||.|..|||.||:||::.|:.|.|:...:|:||.|
Mouse   165 ATEEIVIVAIQYRLGVLGFFSTGDQHAR--GNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVS 227

  Fly   197 AGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFR-LAQQNGFTGENDDAKVLEYL 260
            |||.|....:.:..::||||.||..||........:...:..:: :|..:|....:.:| ::..|
Mouse   228 AGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANLSGCEATDSEA-LIHCL 291

  Fly   261 QGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTS 325
            :....::::..|          .:|...|.|  ..||  .:||.|.|:......:..|.::|..:
Mouse   292 RAKSKQEILAIN----------QVFKMIPAV--VDGE--FLPKHPQELLTSMDFHPVPSIIGVNT 342

  Fly   326 FE---GLFMY---------------PAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQR 372
            .|   |:.|:               |||..|..|...|..:.:.|:..:....:.:.|.|:...|
Mouse   343 DECGWGVPMFMGLDHIIKNITRETLPAVLKNTAARMMLPPECSHLLVEEYMGDTEDPETLQAQFR 407

  Fly   373 LMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAK 437
            .|...|.:..|:.::                      |....::||.|:|.|...|......|.
Mouse   408 EMLGDFMFVIPALQV----------------------AHFQRSQAPVYFYEFQHLSSFIKHVRP- 449

  Fly   438 FCGDKIKTGVAHADDLSYLFRNAGSW----KLDKTSAEYRTIERMIGIWTAFAATSNPNCPEIGH 498
               ..:|..  |.||::::|   ||:    .||.|..|......|:..|..||...|||..  |.
Mouse   450 ---SHVKAD--HGDDVAFVF---GSYLWDMNLDLTEEEELLKRMMMKYWANFARNGNPNSE--GL 504

  Fly   499 LEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIW 533
            ..| |...:| ::.:.:.:...:....:..:||.|
Mouse   505 PSW-PVLDHD-EQYLQLDTQPAVGRALKARRLQFW 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	149/530 (28%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	151/553 (27%)
		Aes	<127..>230	CDD:223730	41/105 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832755
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640