Protein Alignment alpha-Est5 and ces2.6

DIOPT Version :10

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_031756661.1
• Gene: ces2.6 / 100493652
• XenbaseID: XB-GENE-6467133
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 162/580 - (27%)
• Similarity: 245/580 - (42%)
• Gaps: 131/580 - (22%)

  Fly    13 LTLPVGQIKGVKRLSL--YDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQ 75
            ||...||:.| |.:::  .|....:|..:||||.|:|.|||..|.|.:|||.:.:.:.......|
 Frog    29 LTTKYGQLLG-KTVNVRGADRHVHAFMGVPFAKAPVGHLRFADPQPPEPWSSIREASVIPPMCLQ 92

  Fly    76 RGL--LTR--EIE-----GGEDCLYLNVYS-KQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDY 130
            .|:  |.:  :||     ..||||||||:: ...|....|||||:|:||...:|.|:. ..|...
 Frog    93 HGMEQLIKLFKIEFVLPASSEDCLYLNVFTPADRKENSKLPVMVFIHGGGLLMGLASM-FDGSAL 156

  Fly   131 FMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGE 195
            ...::||:|::.||:..|||.|..|.  :..||.|..|||.|||||::.|..|.||..::|:||:
 Frog   157 SGYENVVVVSIQYRLGILGFFSTGDK--EAQGNFGFLDQVAALKWVQENIKEFGGDPESVTIFGQ 219

  Fly   196 SAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDD-----AK 255
            ||||.|....:.:..::||||:||..||                 :|...|......:     ..
 Frog   220 SAGGLSVSTHVLSPLSKGLFHRAIAESG-----------------VALLPGLVVSKTEEVLFVRD 267

  Fly   256 VLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCV----VPKPPVEMARDAWSNN 316
            ::..|.|...:.||:......|..    :.|...|::......||    :|||..|:..:..||.
 Frog   268 LVASLSGCNIKGLVDCLKKKTEEE----IMAISATMQFTALPACVDGVFLPKPVEEILANKESNR 328

  Fly   317 FPVMLGGTSFEGLFMYP------------------AVSANLKALDSLSQDPTRLVPVDVRTVSSE 363
            .|.::|..:.|..:|.|                  :|.:.|..|.|:|.    |||:
 Frog   329 VPFLIGFNNNEFGWMLPMALNISGFREGMGRKEVQSVLSALPLLHSVSS----LVPL-------- 381

  Fly   364 KENLEYSQRLMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAK---APTYYYRFD 425
                     |||.|||.:...:|:....|:.....:|.....||    ..|.:   .|.|.|.|.
 Frog   382 ---------LMKEYFGDTNDQTEIRNKFLELNGDILFVIPALRT----AQYHRDSGLPVYLYEFQ 433

  Fly   426 -----FDSPNFNFYRAKFCGDKIKTGVAHADDLSYL----FRNAGS-WKLDKTSAEYRTIERMIG 480
                 :|:...:|.:|.           |.|:|.::    |.|..: ::.|.|..|....:.|:.
 Frog   434 HRPSLYDNSKDDFVKAD-----------HGDELYFVLGGPFLNGDAIFQSDGTDEEKNLSKTMMK 487

  Fly   481 IWTAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTIIDLPEYE-------KLQIW 533
            .|..||...:||.|  |.:|| |:...|        .|...|:|.:..       :|:.|
 Frog   488 YWANFARNGDPNGP--GLVEW-PAYDED--------KDYLEINLKQKSSWRLKEGRLKFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	161/578 (28%)
ces2.6	XP_031756661.1	COesterase	27..536	CDD:395084	161/578 (28%)