Protein Alignment alpha-Est5 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 626
• Identity: 160/626 - (25%)
• Similarity: 266/626 - (42%)
• Gaps: 150/626 - (23%)

  Fly     7 SLETCE-----------LTLPVGQIKGVKRLSLYDD---PYFSFEKIPFAKPPLGELRFRAPVPA 57
            :|.:|:           :|...|:::||:: .|.::   |...:..:|:|.||:||.||:.|...
Zfish    37 ALSSCQRADLTTAKHPMVTTGYGKLRGVRK-ELNNEILGPVEQYLGVPYATPPVGERRFQPPEAP 100

  Fly    58 DPWSGVLDCTHYAEKPTQ--RGLL---------TREIEG--------GEDCLYLNVY-------- 95
            ..|..:.:.|.:|....|  .|:|         |..::.        .|||||||||
Zfish   101 GSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPL 165

  Fly    96 -------------SKQLKSEKPLPVMVYIYGGAFTVG------EATRELYGPDYFMTKDVVLVTL 141
                         .:.::..:..|||::|:||:|..|      .:....||       :|::||:
Zfish   166 TKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASVLAAYG-------NVIVVTM 223

  Fly   142 NYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMM 206
            |||:..|||||..|.|.|  ||.||.||:.||:|:.:.|.:|.||...||:||..||....:.::
Zfish   224 NYRLGVLGFLSSGDQSAK--GNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLI 286

  Fly   207 CTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFR-------LAQQNGFTGENDDAKVLEYLQGVP 264
            .:..:.|||.:||..||:..:.|:.|      :|       ||::.| ...:|.|.:::.|:...
Zfish   287 LSHHSEGLFQRAIAQSGSAISSWSVN------YRPLMYTKILAKKVG-CSYSDTADLVDCLRRKS 344

  Fly   265 ARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFEGL 329
            .|:||:.::....:.     .||||.|:   |:  |||..|..:.:.....|:.::||....|||
Zfish   345 YRELVDQDVQPARYH-----IAFGPVVD---GD--VVPDDPEILMQQGEFLNYDILLGVNQGEGL 399

  Fly   330 FMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNMLDF 394
            ....         |:..::.......|. |:|:..:||          :|| |...::|...:.|
Zfish   400 KFVD---------DNEGEEGISAASFDY-TISNFVDNL----------YGY-PEGKDILRETIKF 443

  Fly   395 YSYKIFWHGFN-----RTFNARLTYAK--AP---TYYYRFDFDSPNFNFYRAKFCGDKIK---TG 446
             .|..:....|     :|..|..|..:  ||   |.....:|.||.:.:.....|..:.:   ..
Zfish   444 -MYTDWADRDNGDMRRKTLLALFTDHQWVAPAVATAKLHAEFQSPVYFYTFHHHCQTEARPEWAD 507

  Fly   447 VAHADDLSYLF--RNAGSWKL-----DKTSAEYRTIERMIGIWTAFAATSNPNCP---EIGHLEW 501
            .||.|::.|:|  ...|:.:|     .|.......:  ::..||.||.|.:||.|   :...:..
Zfish   508 AAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAV--VMTYWTNFAKTGDPNIPVPQDTKFIHT 570

  Fly   502 KPS-------TK--NDPKRVINISSDVTIIDLPEYEKLQIW 533
            ||:       ||  :..|:.::|.....|.|.....|:..|
Zfish   571 KPNRFEEVIWTKFSSKDKQYLHIGLKPRIRDNYRANKVAFW 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est5	NP_001246965.1	COesterase	7..510	CDD:278561	154/601 (26%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	157/614 (26%)
		Aes	<181..>279	CDD:223730	42/106 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740