Protein Alignment alphaTub84D and TUB2

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_116616.1
• Gene: TUB2 / 850506
• SGDID: S000001857
• Length: 457
• Species: Saccharomyces cerevisiae
• Alignment Length: 438
• Identity: 181/438 - (41%)
• Similarity: 263/438 - (60%)
• Gaps: 18/438 - (4%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDD----SFNTFFSETGAGKH 61
            |||.|.|..||.|.|||.|.||..|.|||:..:|      |..|.||    ..|.:|:|..:||.
Yeast     1 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNG------TYHGHDDIQKERLNVYFNEASSGKW 59

  Fly    62 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 126
            |||::.|||||..:|.||......||.|:..|.|:..|.|.:|:||||.|.|:||.|:|.||:.|
Yeast    60 VPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREA 124

  Fly   127 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTT 191
            :.|..||||.|.||.|||||||..:||:.::..::..:....|:|.|:|:.|..||||||:.|:.
Yeast   125 EGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSV 189

  Fly   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256
            |..:||||..|.:||||:||||:|.|.:.:|:|.:||.|:..::|.:|.|||:.|.||.||.:..
Yeast   190 HQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLA 254

  Fly   257 TNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRG 321
            .||||:||:||.:|.|||:.:........|:|.|:|...|:..|.|...|||:|:|:.....:||
Yeast   255 VNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRG 319

  Fly   322 DVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            .|..|:|...:..:::|.:..||:|.|...:..:    .:|.|.|    :..|...::|:|:|.|
Yeast   320 KVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAV----CSVAPQG----LDMAATFIANSTSIQE 376

  Fly   387 AWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 434
            .:.|:..:|..|:.::||:|||..|||:|.|||||..::..|..:|::
Yeast   377 LFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQ 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	181/438 (41%)
TUB2	NP_116616.1	beta_tubulin	2..426	CDD:276956	180/437 (41%)