Protein Alignment alphaTub84D and Tubb4b

DIOPT Version :10

• Sequence 1: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_666228.1
• Gene: Tubb4b / 227613
• MGIID: 1915472
• Length: 445
• Species: Mus musculus
• Alignment Length: 453
• Identity: 183/453 - (40%)
• Similarity: 270/453 - (59%)
• Gaps: 18/453 - (3%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDD----SFNTFFSETGAGKH 61
            |||.:.:..||.|.|||...||:...||||.|.|      |..|..|    ..|.:::|...||:
Mouse     1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTG------TYHGDSDLQLERINVYYNEATGGKY 59

  Fly    62 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 126
            |||||.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|
Mouse    60 VPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124

  Fly   127 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTT 191
            :.|..||||.:.||.|||||||..:||:.::..:|..:....|:|.|:|:||..||||||:.|:.
Mouse   125 ESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189

  Fly   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256
            |..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:..
Mouse   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254

  Fly   257 TNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRG 321
            .|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|...|||||:|:....::||
Mouse   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 319

  Fly   322 DVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            .:..|:|:..:..::.|.:..||:|.|...|..:...||        ..::.:...:.|:|||.|
Mouse   320 RMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFIGNSTAIQE 376

  Fly   387 AWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEE 449
            .:.|:..:|..|:.::||:|||.||||:|.||:||..::..|..:|::....:.:.|||..||
Mouse   377 LFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEE 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	178/441 (40%)
Tubb4b	NP_666228.1	PLN00220	1..427	CDD:215107	178/439 (41%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	426..445		5/14 (36%)