DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rtnl2 and rtn1

DIOPT Version :9

Sequence 1:	NP_001246964.1	Gene:	Rtnl2 / 40903	FlyBaseID:	FBgn0015831	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001078819.2	Gene:	rtn1 / 677736	XenbaseID:	XB-GENE-1011333	Length:	764	Species:	Xenopus tropicalis

Alignment Length:	188	Identity:	59/188 - (31%)
Similarity:	98/188 - (52%)	Gaps:	10/188 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LLLWRNSRKTLIVFTGILLLLLDVMVHSVISVISMVGITVLIAAIGHRL---LVQFWSIWKKDEN 83
            ||.||:.::|.|||..:||:|..:...||:|||:.:.:..|.|.|..|:   ::|  ::.|.||.
Frog   581 LLYWRDIKQTGIVFGSVLLMLFSLTQFSVVSVIAYLALAALSATISFRIYKSVLQ--AVQKTDEG 643

  Fly    84 KDQILRFYPHPKIEIPREETLYLAGKAVSHINLILNRMIELLLVEKWEDSLKFLVLLCGINLLGD 148
            ..  .:.|...:|.:.:|:.........::.|.|:..:..|.||:...|||||.||:..:..:|.
Frog   644 HP--FKSYLDMEISLSQEQIQKYTDCLQAYTNSIVKELRRLFLVQDLVDSLKFAVLMWLLTYVGA 706

  Fly   149 CFNGLTLLIFGHLFIFTVPKLYESYKPFVDVQ---IRKFRKCKIDKSNVEKPICIQKE 203
            .||||||||...:.:|::|.:|:.|:..:|..   :|......:.|...:.|...|||
Frog   707 LFNGLTLLIMAVVSMFSLPVVYDKYQAQIDQYLGLVRTNMNTIVTKIQAKIPGTKQKE 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl2	NP_001246964.1	Reticulon	21..183	CDD:280592	53/166 (32%)
rtn1	NP_001078819.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	115..147
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	247..400
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	455..475
		Reticulon	580..742	CDD:367092	53/164 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910